Rekombinanter Spectrin, Beta, Non-erythrocytic 2 (SPTBN2) (AA 356-475) Antikörper
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- Target Alle Spectrin, Beta, Non-erythrocytic 2 (SPTBN2) Antikörper anzeigen
- Spectrin, Beta, Non-erythrocytic 2 (SPTBN2)
- Antikörpertyp
- Recombinant Antibody
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Bindungsspezifität
- AA 356-475
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Monoklonal
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Konjugat
- Unkonjugiert
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Applikation
- Western Blotting (WB), Flow Cytometry (FACS), ELISA, Coating (Coat), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
- Spezifität
- Spectrin is an actin binding protein that is a major component of the plasma membrane skeleton. Spectrins function as membrane organizers and stabilizers by forming dimers, tetramers and higher polymers. Vertebrate spectrins have two alpha-subunits (alpha-I/alpha-II) four beta-subunits (beta-I-beta-IV) and a beta-H subunit creating diversity and specialization of function. Spectrin III is highly expressed in brain, kidney, pancreas and liver, and at lower levels in lung and placenta. Spectrin beta 3 is primarily expressed in nervous tissues with highest expression levels in the cerebellum, where it is found in Purkinje cell soma and dendrites.
- Kreuzreaktivität (Details)
- Human.
- Aufreinigung
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- Immunogen
- Recombinant human SPTBN2 fragment (aa356-475) (exact sequence is proprietary)
- Klon
- SPTBN2-2894R
- Isotyp
- IgG
- Top Product
- Discover our top product SPTBN2 Primärantikörper
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- Applikationshinweise
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Known_Application: Flow Cytometry (1-2 μg/million cells), (ELISA (Use Ab at 2-4 μg/mL for coating) (Order Ab without BSA),Western Blot (1-2 μg/mL),Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT) (Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.
Positive_Control: HeLa cells. Pancreas or Liver.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1.0 mg/mL
- Buffer
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- Konservierungsmittel
- Azide free
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- Haltbarkeit
- 24 months
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- Target
- Spectrin, Beta, Non-erythrocytic 2 (SPTBN2)
- Andere Bezeichnung
- SPTBN2 (SPTBN2 Produkte)
- Synonyme
- Spnb3 antikoerper, mKIAA0302 antikoerper, GTRAP41 antikoerper, SCA5 antikoerper, spectrin beta, non-erythrocytic 2 antikoerper, spectrin, beta, non-erythrocytic 2 antikoerper, Sptbn2 antikoerper, SPTBN2 antikoerper
- Hintergrund
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Beta III spectrin, SCA5, Spectrin beta chain brain 2, Spectrin beta non-erythrocytic 2, Spectrin non-erythroid beta chain 2, Spinocerebellar ataxia 5, SPTBN2,Spectrin beta III (SPTBN2)
Cellular localisation: Cell Surface - Molekulargewicht
- 246kDa
- Gen-ID
- 6712, 26915
- UniProt
- O15020
- Pathways
- Regulation of Actin Filament Polymerization, Synaptic Vesicle Exocytosis
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