Uroplakin 3A Antikörper (AA 260-279)

Produktnummer ABIN6938735

Produktdetails anti-Uroplakin 3A Antikörper

Target: Uroplakin 3A (UPK3A)

Bindungsspezifität: AA 260-279

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Uroplakin 3A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Spezifität: Uroplakin-3A (UPK3A) is a component of the asymmetric unit membrane (AUM). It is a highly specialized bio-membrane made by terminally differentiated urothelial cells. The protein may play an important role in AUM-cytoskeleton interaction in terminally differentiated urothelial cells. UPK3A also contributes to the formation of urothelial glycocalyx, which may play an important role in preventing bacterial adherence through FimH bacterial protein binding leading to bladder infection. UPK3A has been shown as a helpful marker for the detection of bladder cancer.

Kreuzreaktivität (Details): Human.

Aufreinigung: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogen: A synthetic peptide, aa260-279 (GASESSYTSVNRGPPLDRAE) of human UPK3A

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

Known_Application: Western Blot (1-2 μg/mL), Optimal dilution for a specific application should be determined.

Positive_Control: HEK293 cells. Bladder carcinoma.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Konservierungsmittel: Azide free

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Haltbarkeit: 24 months

Details zu Uroplakin 3A

Target: Uroplakin 3A (UPK3A)

Andere Bezeichnung: UPK3A (UPK3A Produkte)

Hintergrund: UP3a, UPIIIA, UPK3A, Uroplakin III (UPIII), Uroplakin3A,Uroplakin 3A (Bladder Carcinoma Marker)
Cellular localisation: Cell surface

Molekulargewicht: 30kDa

Gen-ID: 7380, 632787

UniProt: O75631