CGB Antikörper

Produktnummer ABIN6939101

Produktdetails anti-CGB Antikörper

Target: CGB (Chorionic Gonadotropin, beta Polypeptide (CGB))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CGB Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Staining Methods (StM)

Spezifität: This MAb reacts with a protein of 22 kDa, identified as beta sub-unit of HCG. It does not cross react with the alpha sub-unit. HCG is a glycoprotein, which is secreted in large quantities by normal trophoblasts. It is present only in trace amounts in non-pregnant urine and sera but rises sharply during pregnancy. HCG is composed of two non-identical, non-covalently linked polypeptide chains designated as the subunit is identical to that of thyroid stimulating hormone (TSH) follicle stimulating hormone (FSH), and luteinizing hormone (LH). hCG MAb detects cells and tumors of trophoblastic origin such as choriocarcinoma. Large cell carcinoma and adenocarcinoma of the lung demonstrate anti-hCG positivity in 90 % and 60 % of cases respectively. 20 % of lung squamous cell carcinomas are positive. hCG expression by non-trophoblastic tumors may indicate aggressive behavior.

Aufreinigung: Purified by Protein A/G

Immunogen: Recombinant full-length hCG beta protein

Klon: HCGb-54

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise:

Positive Control: JAR or TT cells. Placenta.

Known Application: Immunohistochemistry (Formalin-fixed) (0.5-1 μg/mL) (Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-80 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu CGB

Target: CGB (Chorionic Gonadotropin, beta Polypeptide (CGB))

Andere Bezeichnung: CGB (CGB Produkte)

Synonyme: CGB antikoerper, CGB3 antikoerper, CGB5 antikoerper, CGB7 antikoerper, CGB8 antikoerper, hCGB antikoerper, CG-beta antikoerper, chorionic gonadotropin, beta polypeptide antikoerper, chorionic gonadotropin beta subunit 3 antikoerper, CGB antikoerper, CGB3 antikoerper

Molekulargewicht: 22kDa

Gen-ID: 1082

UniProt: P01233