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TOP1MT Antikörper

TOP1MT Reaktivität: Human IHC, StM Wirt: Maus Monoclonal TOP1MT-568 unconjugated
Produktnummer ABIN6939148
  • Target Alle TOP1MT Antikörper anzeigen
    TOP1MT (Topoisomerase (DNA) I, Mitochondrial (TOP1MT))
    Reaktivität
    • 28
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 19
    • 11
    Maus
    Klonalität
    • 17
    • 13
    Monoklonal
    Konjugat
    • 14
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser TOP1MT Antikörper ist unkonjugiert
    Applikation
    • 11
    • 10
    • 10
    • 10
    • 6
    • 4
    • 2
    • 2
    Immunohistochemistry (IHC), Staining Methods (StM)
    Aufreinigung
    Purified by Protein A/G
    Immunogen
    Recombinant full-length human TOP1MT protein
    Klon
    TOP1MT-568
    Isotyp
    IgG1 kappa
    Top Product
    Discover our top product TOP1MT Primärantikörper
  • Applikationshinweise

    Positive Control: A431 cells. Heart, Skeletal muscle, brain or fetal liver.

    Known Application: Immunohistochemistry (Formalin-fixed) (0.5-1 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    200 μg/mL
    Buffer
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-80 °C
    Informationen zur Lagerung
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    Haltbarkeit
    24 months
  • Target
    TOP1MT (Topoisomerase (DNA) I, Mitochondrial (TOP1MT))
    Andere Bezeichnung
    TOP1MT (TOP1MT Produkte)
    Synonyme
    2900052H09Rik antikoerper, TOP1 antikoerper, topoisomerase (DNA) I, mitochondrial antikoerper, DNA topoisomerase 1, mitochondrial antikoerper, DNA topoisomerase I mitochondrial antikoerper, TOP1MT antikoerper, Top1mt antikoerper
    Hintergrund
    DNA topoisomerases are nuclear enzymes that regulate the topological structure of DNA in eukaryotic cells by transiently breaking and rejoining DNA strands. Due to their roles in DNA replication, recombination, and transcription, DNA topoisomerases have been identified as targets of numerous anticancer drugs. Mitochondrial Topo I (DNA topoisomerase I, mitochondrial) is a 601 amino acid protein that primarily acts to relieve DNA strain that may occur during duplication of mitochondrial DNA. As a type IB topoisomerase, mitochondrial Topo I requires a divalent metal, either, calcium or magnesium, as well as an alkaline pH for optimal activity.
    Molekulargewicht
    70kDa
    Gen-ID
    116447
    UniProt
    Q969P6
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