DNMT1 Antikörper (AA 767-912)
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- Target Alle DNMT1 Antikörper anzeigen
- DNMT1 (DNA (Cytosine-5)-Methyltransferase 1 (DNMT1))
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Bindungsspezifität
- AA 767-912
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser DNMT1 Antikörper ist unkonjugiert
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Applikation
- Immunohistochemistry (IHC), Immunostaining (ISt), Staining Methods (StM)
- Aufreinigung
- Purified by Protein A/G
- Immunogen
- Recombinant human DNMT1 protein fragment (around aa 767-912) (exact sequence is proprietary)
- Klon
- DNMT1-2061
- Isotyp
- IgG2b kappa
- Top Product
- Discover our top product DNMT1 Primärantikörper
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- Applikationshinweise
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Positive Control: Raji cells. Tonsil or Placenta.
Known Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues is enhanced by boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 200 μg/mL
- Buffer
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-80 °C
- Informationen zur Lagerung
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Haltbarkeit
- 24 months
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- Target
- DNMT1 (DNA (Cytosine-5)-Methyltransferase 1 (DNMT1))
- Andere Bezeichnung
- DNMT1 (DNMT1 Produkte)
- Hintergrund
- This gene encodes an enzyme that transfers methyl groups to cytosine nucleotides of genomic DNA. This protein is the major enzyme responsible for maintaining methylation patterns following DNA replication and shows a preference for hemi-methylated DNA. Methylation of DNA is an important component of mammalian epigenetic gene regulation. Aberrant methylation patterns are found in human tumors and associated with developmental abnormalities. Variation in this gene has been associated with cerebellar ataxia, deafness, and narcolepsy, and neuropathy, hereditary sensory, type IE.
- Molekulargewicht
- 184kDa
- Gen-ID
- 1786
- UniProt
- P26358
- Pathways
- SARS-CoV-2 Protein Interaktom, Phosphorylierungen bei SARS-CoV-2 Infektion
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