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Desmoglein 3 Antikörper (AA 379-491)

DSG3 Reaktivität: Human WB, ELISA, Coat Wirt: Maus Monoclonal DSG3-2796 unconjugated
Produktnummer ABIN6939272
  • Target Alle Desmoglein 3 (DSG3) Antikörper anzeigen
    Desmoglein 3 (DSG3)
    Bindungsspezifität
    • 15
    • 8
    • 7
    • 7
    • 7
    • 5
    • 5
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 379-491
    Reaktivität
    • 69
    • 21
    • 16
    Human
    Wirt
    • 63
    • 26
    Maus
    Klonalität
    • 62
    • 27
    Monoklonal
    Konjugat
    • 38
    • 9
    • 8
    • 7
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Desmoglein 3 Antikörper ist unkonjugiert
    Applikation
    • 66
    • 35
    • 20
    • 18
    • 16
    • 13
    • 13
    • 8
    • 7
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Coating (Coat)
    Spezifität
    Recognizes a protein of 130 kDa, identified as Desmoglein-3 (DSG3). This MAb is highly specific to Desmoglein-3 and does not cross-react with other members of the Desmoglein-family. DSG3 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Research has shown that DSG3 has a very high sensitivity (80 % ) and specificity (100 %) in recognizing squamous cell carcinoma (SqCC). Therefore, DSG3 is considered a very important marker for lung SqCC and can be a useful ancillary marker to separate SqCC from other subtypes of lung cancer. Moreover, studies have shown that DSG3 expression in lung SqCC may indicate a poor prognosis.
    Aufreinigung
    Purified by Protein A/G
    Immunogen
    Recombinant fragment (around aa 379-491) human DSG3 protein (exact sequence is proprietary)
    Klon
    DSG3-2796
    Isotyp
    IgG2b kappa
    Top Product
    Discover our top product DSG3 Primärantikörper
  • Applikationshinweise

    Positive Control: A431 cells. Skin or Lung Squamous Cell Carcinoma (SCC).

    Known Application: ELISA (For coating, order Ab without BSA), Western Blot (1-2 μg/mL)Optimal dilution for a specific application should be determined.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    200 μg/mL
    Buffer
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-80 °C
    Informationen zur Lagerung
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    Haltbarkeit
    24 months
  • Target
    Desmoglein 3 (DSG3)
    Andere Bezeichnung
    DSG3 (DSG3 Produkte)
    Synonyme
    DSG3 antikoerper, CDHF6 antikoerper, PVA antikoerper, bal antikoerper, balding antikoerper, desmoglein 3 antikoerper, DSG3 antikoerper, Dsg3 antikoerper
    Molekulargewicht
    130kDa
    Gen-ID
    1830
    UniProt
    P32926
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