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Estrogen Receptor alpha Antikörper (AA 129-312)

ESR1 Reaktivität: Human IHC, IF, FACS, StM Wirt: Maus Monoclonal ESR1-3557 unconjugated
Produktnummer ABIN6939346
  • Target Alle Estrogen Receptor alpha (ESR1) Antikörper anzeigen
    Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))
    Bindungsspezifität
    • 30
    • 30
    • 28
    • 26
    • 22
    • 21
    • 21
    • 16
    • 16
    • 16
    • 16
    • 15
    • 15
    • 15
    • 13
    • 12
    • 11
    • 10
    • 9
    • 9
    • 8
    • 7
    • 7
    • 7
    • 6
    • 6
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    AA 129-312
    Reaktivität
    • 474
    • 171
    • 165
    • 18
    • 18
    • 10
    • 7
    • 7
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    Human
    Wirt
    • 386
    • 95
    • 2
    • 1
    Maus
    Klonalität
    • 373
    • 113
    Monoklonal
    Konjugat
    • 211
    • 35
    • 22
    • 22
    • 18
    • 10
    • 9
    • 9
    • 9
    • 9
    • 9
    • 9
    • 8
    • 8
    • 8
    • 8
    • 8
    • 8
    • 8
    • 8
    • 8
    • 8
    • 8
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 1
    • 1
    Dieser Estrogen Receptor alpha Antikörper ist unkonjugiert
    Applikation
    • 355
    • 166
    • 139
    • 116
    • 94
    • 86
    • 80
    • 53
    • 32
    • 28
    • 23
    • 15
    • 8
    • 7
    • 6
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS), Staining Methods (StM)
    Spezifität
    This monoclonal antibody is specific to estrogen receptor alpha (ER alpha) and shows minimal cross-reaction with other members of the family. ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response to anti-estrogen (e.g. tamoxifen) therapy. It strongly stains nuclei of epithelial cells in breast carcinomas.
    Aufreinigung
    Purified by Protein A/G
    Immunogen
    Recombinant fragment (around aa129-312) of human ESR1 protein (exact sequence is proprietary)
    Klon
    ESR1-3557
    Isotyp
    IgG1 kappa
    Top Product
    Discover our top product ESR1 Primärantikörper
  • Applikationshinweise

    Positive Control: MCF-7 cells (IF). Human breast or endometrial carcinoma (IHC).

    Known Application: Immunofluorescence (1-2 μg/mL), Flow Cytometry (1-2 μg/million cells),Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    200 μg/mL
    Buffer
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store at 2 to 8°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    Haltbarkeit
    24 months
  • Target
    Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))
    Andere Bezeichnung
    ESR1 (ESR1 Produkte)
    Synonyme
    LOC398734 antikoerper, AA420328 antikoerper, AU041214 antikoerper, ER-alpha antikoerper, ER[a] antikoerper, ERa antikoerper, ERalpha antikoerper, ESR antikoerper, Estr antikoerper, Estra antikoerper, Nr3a1 antikoerper, NR3A1 antikoerper, eralpha antikoerper, zfER[a] antikoerper, ER antikoerper, ESRA antikoerper, ESTRR antikoerper, Era antikoerper, akap12 antikoerper, cb27 antikoerper, esr1 antikoerper, fb72g12 antikoerper, id:ibd1202 antikoerper, sb:cb27 antikoerper, si:ch73-192g21.1 antikoerper, wu:fb72g12 antikoerper, wu:fc21c03 antikoerper, Esr antikoerper, RNESTROR antikoerper, ERALPHA antikoerper, er antikoerper, esr antikoerper, nr3a1 antikoerper, XER antikoerper, era antikoerper, esra antikoerper, ERbeta antikoerper, xesr-1 antikoerper, xlERalpha1 antikoerper, xlERalpha2 antikoerper, ESR1 antikoerper, estrogen receptor 1 L homeolog antikoerper, estrogen receptor 1 (alpha) antikoerper, estrogen receptor 1 antikoerper, A kinase (PRKA) anchor protein 12b antikoerper, esr1.L antikoerper, Esr1 antikoerper, ESR1 antikoerper, esr1 antikoerper, akap12b antikoerper
    Molekulargewicht
    ~67kDa
    Gen-ID
    2099
    UniProt
    P03372
    Pathways
    Nuclear Receptor Transcription Pathway, EGFR Signaling Pathway, Retinoic Acid Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly
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