Estrogen Receptor alpha Antikörper (AA 129-312)
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- Target Alle Estrogen Receptor alpha (ESR1) Antikörper anzeigen
- Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))
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Bindungsspezifität
- AA 129-312
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser Estrogen Receptor alpha Antikörper ist unkonjugiert
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Applikation
- Immunohistochemistry (IHC), Flow Cytometry (FACS), Staining Methods (StM)
- Spezifität
- This monoclonal antibody is specific to estrogen receptor alpha (ER alpha) and shows minimal cross-reaction with other members of the family. ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response to anti-estrogen (e.g. tamoxifen) therapy. It strongly stains nuclei of epithelial cells in breast carcinomas.
- Aufreinigung
- Purified by Protein A/G
- Immunogen
- Recombinant human ESR1 protein fragment (around aa129-312) (exact sequence is proprietary)
- Klon
- ESR1-3559
- Isotyp
- IgG2b kappa
- Top Product
- Discover our top product ESR1 Primärantikörper
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anti-Estrogen Receptor 1 (ESR1) (AA 246-273) antibody
ESR1 Reaktivität: Human, Maus WB, IF, IHC (p) Wirt: Kaninchen Polyclonal RB33807 unconjugated
anti-Estrogen Receptor 1 (ESR1) (AA 129-312) antibodyESR1 Reaktivität: Human IHC, IF, FACS, StM Wirt: Maus Monoclonal ESR1-3557 unconjugated
anti-Estrogen Receptor 1 (ESR1) (AA 2-185) antibodyESR1 Reaktivität: Human WB, IHC, ELISA, FACS, ICC Wirt: Maus Monoclonal 6A6E8 unconjugated
anti-Estrogen Receptor 1 (ESR1) antibodyESR1 Reaktivität: Human WB, IHC, StM Wirt: Maus Monoclonal ESR1-1904 unconjugated
anti-Estrogen Receptor 1 (ESR1) (pSer167) antibodyESR1 Reaktivität: Human, Ratte ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Estrogen Receptor 1 (ESR1) (AA 2-185) antibodyESR1 Reaktivität: Human WB, IHC, FACS, StM Wirt: Maus Monoclonal ER506 unconjugated
anti-Estrogen Receptor 1 (ESR1) (C-Term) antibodyESR1 Reaktivität: Human, Maus, Ratte WB, IHC, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Estrogen Receptor 1 (ESR1) (AA 246-273) antibodyESR1 Reaktivität: Human WB, IHC, ELISA, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Estrogen Receptor 1 (ESR1) (AA 233-483) antibodyESR1 Reaktivität: Maus WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Estrogen Receptor 1 (ESR1) (pSer118) antibodyESR1 Reaktivität: Human, Maus, Ratte WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
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Positive Control: MCF-7 cells. Breast or Endometrial Carcinoma (IHC).
Known Application: Flow Cytometry (1-2 μg/million cells),Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 200 μg/mL
- Buffer
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C
- Informationen zur Lagerung
- Store at 2 to 8°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Haltbarkeit
- 24 months
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- Target
- Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))
- Andere Bezeichnung
- ESR1 (ESR1 Produkte)
- Molekulargewicht
- ~67kDa
- Gen-ID
- 2099
- UniProt
- P03372
- Pathways
- Nuclear Receptor Transcription Pathway, EGFR Signaling Pathway, Retinoic Acid Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly
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