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FAT Atypical Cadherin 2 (FAT2) Antikörper

FAT2 Reaktivität: Human IF, FACS, IHC, StM Wirt: Maus Monoclonal 8C5 unconjugated
Produktnummer ABIN6939371
  • Target Alle FAT Atypical Cadherin 2 (FAT2) Antikörper anzeigen
    FAT Atypical Cadherin 2 (FAT2)
    Reaktivität
    • 14
    • 1
    • 1
    Human
    Wirt
    • 9
    • 5
    Maus
    Klonalität
    • 9
    • 5
    Monoklonal
    Konjugat
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Unkonjugiert
    Applikation
    • 10
    • 9
    • 9
    • 3
    • 1
    • 1
    • 1
    Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (IHC), Staining Methods (StM)
    Spezifität
    Recognizes a protein of 480 kDa, which is identified as FAT2. The cadherins represent a family of Ca2+-dependent adhesion molecules that function to mediate cell-to-cell binding that is critical for the maintenance of structure and morphogenesis. Cadherins each contain a large extracellular domain at the N-terminus, which is characterized by a series of five homologous repeats, the most distal of which is thought to be responsible for binding specificity. The relatively short C-terminal intracellular domain interacts with a variety of cytoplasmic proteins, including -catenin, to regulate cadherin function. The cadherin superfamily includes cadherins, protocadherins, desmogleins and desmocollins. FAT2 (FAT tumor suppressor homolog 2) is a single-pass type I membrane protein that belongs to the protocadherin subfamily of cadherins. FAT2 contains one Laminin G-like domain, two EGF-like domains and 32 cadherin domains and is believed to function as a cell adhesion molecule, controlling cell proliferation and playing an important role in cerebellum development.
    Aufreinigung
    Purified by Protein A/G
    Immunogen
    Purified recombinant human FAT2 fusion protein.
    Klon
    8C5
    Isotyp
    IgG1 kappa
    Top Product
    Discover our top product FAT2 Primärantikörper
  • Applikationshinweise

    Positive Control: Esophagus, Cervix, Uterus, Tonsil or Cerebellum.

    Known Application: Flow Cytometry (0.5-1 μg/million cells), Immunofluorescence (1-2 μg/mL), Immunohistochemistry (Formalin-fixed) (0.5-1 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    200 μg/mL
    Buffer
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-80 °C
    Informationen zur Lagerung
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    Haltbarkeit
    24 months
  • Target
    FAT Atypical Cadherin 2 (FAT2)
    Andere Bezeichnung
    FAT2 (FAT2 Produkte)
    Synonyme
    EMI2 antikoerper, Fath2 antikoerper, Gm523 antikoerper, mKIAA0811 antikoerper, CDHF8 antikoerper, CDHR9 antikoerper, HFAT2 antikoerper, MEGF1 antikoerper, FAT atypical cadherin 2 antikoerper, Fat2 antikoerper, FAT2 antikoerper
    Molekulargewicht
    480kDa
    Gen-ID
    2196
    UniProt
    Q9NYQ8
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