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Rekombinanter Filaggrin Antikörper (AA 198-288)

FLG Reaktivität: Human IHC, ISt, StM Wirt: Maus Monoclonal rFLG-1561 unconjugated Recombinant Antibody
Produktnummer ABIN6939387
  • Target Alle Filaggrin (FLG) Antikörper anzeigen
    Filaggrin (FLG)
    Antikörpertyp
    Recombinant Antibody
    Bindungsspezifität
    • 16
    • 9
    • 8
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 198-288
    Reaktivität
    • 65
    • 19
    • 13
    Human
    Wirt
    • 49
    • 23
    Maus
    Klonalität
    • 44
    • 28
    Monoklonal
    Konjugat
    • 43
    • 9
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Filaggrin Antikörper ist unkonjugiert
    Applikation
    • 39
    • 32
    • 25
    • 25
    • 14
    • 12
    • 9
    • 7
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Immunohistochemistry (IHC), Immunostaining (ISt), Staining Methods (StM)
    Aufreinigung
    Purified by Protein A/G
    Immunogen
    Recombinant human Filaggrin protein fragment (aa 198-288) (exact sequence is proprietary)
    Klon
    RFLG-1561
    Isotyp
    IgG1 kappa
    Top Product
    Discover our top product FLG Primärantikörper
  • Applikationshinweise

    Positive Control: U-251-MG cells. Skin.

    Known Application: Immunohistochemistry (Formalin-fixed) (0.5-1 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues is enhanced by boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    200 μg/mL
    Buffer
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-80 °C
    Informationen zur Lagerung
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    Haltbarkeit
    24 months
  • Target
    Filaggrin (FLG)
    Andere Bezeichnung
    FLG (FLG Produkte)
    Synonyme
    AW107830 antikoerper, ft antikoerper, FLG antikoerper, ATOD2 antikoerper, Pflg antikoerper, Flg antikoerper, filaggrin antikoerper, Flg antikoerper, FLG antikoerper, LOC100351762 antikoerper, LOC100728006 antikoerper
    Hintergrund
    Filaggrin is an intermediate filament-associated protein that aggregates keratin intermediate filaments in mammalian epidermis. It is initially synthesized as a polyprotein precursor, profilaggrin (consisting of multiple filaggrin units of 324 aa each), which is localized in keratohyalin granules, and is subsequently proteolytically processed into individual functional filaggrin molecules.Active filaggrin is present at a level of the epidermis where keratinocytes are in transition between the live nucleated granular layer and the anucleate cornified layer, suggesting that filaggrin aids in the terminal differentiation process by facilitating apoptotic machinery.
    Molekulargewicht
    26-45kDa (Processed), 350kDa (Profilaggrin)
    Gen-ID
    2312
    UniProt
    P20930
    Pathways
    Sensory Perception of Sound, Stem Cell Maintenance
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