Rekombinanter Filaggrin Antikörper (AA 198-288)
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- Target Alle Filaggrin (FLG) Antikörper anzeigen
- Filaggrin (FLG)
- Antikörpertyp
- Recombinant Antibody
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Bindungsspezifität
- AA 198-288
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser Filaggrin Antikörper ist unkonjugiert
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Applikation
- Immunohistochemistry (IHC), Immunostaining (ISt), Staining Methods (StM)
- Aufreinigung
- Purified by Protein A/G
- Immunogen
- Recombinant human Filaggrin protein fragment (aa 198-288) (exact sequence is proprietary)
- Klon
- RFLG-1561
- Isotyp
- IgG1 kappa
- Top Product
- Discover our top product FLG Primärantikörper
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- Applikationshinweise
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Positive Control: U-251-MG cells. Skin.
Known Application: Immunohistochemistry (Formalin-fixed) (0.5-1 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues is enhanced by boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 200 μg/mL
- Buffer
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-80 °C
- Informationen zur Lagerung
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Haltbarkeit
- 24 months
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- Target
- Filaggrin (FLG)
- Andere Bezeichnung
- FLG (FLG Produkte)
- Synonyme
- AW107830 antikoerper, ft antikoerper, FLG antikoerper, ATOD2 antikoerper, Pflg antikoerper, Flg antikoerper, filaggrin antikoerper, Flg antikoerper, FLG antikoerper, LOC100351762 antikoerper, LOC100728006 antikoerper
- Hintergrund
- Filaggrin is an intermediate filament-associated protein that aggregates keratin intermediate filaments in mammalian epidermis. It is initially synthesized as a polyprotein precursor, profilaggrin (consisting of multiple filaggrin units of 324 aa each), which is localized in keratohyalin granules, and is subsequently proteolytically processed into individual functional filaggrin molecules.Active filaggrin is present at a level of the epidermis where keratinocytes are in transition between the live nucleated granular layer and the anucleate cornified layer, suggesting that filaggrin aids in the terminal differentiation process by facilitating apoptotic machinery.
- Molekulargewicht
- 26-45kDa (Processed), 350kDa (Profilaggrin)
- Gen-ID
- 2312
- UniProt
- P20930
- Pathways
- Sensory Perception of Sound, Stem Cell Maintenance
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