Rekombinanter FTL Antikörper (AA 38-165)

Produktnummer ABIN6939463

Produktdetails anti-FTL Antikörper

Target: FTL (Ferritin, Light Polypeptide (FTL))

Antikörpertyp: Recombinant Antibody

Bindungsspezifität: AA 38-165

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser FTL Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Staining Methods (StM)

Aufreinigung: Purified by Protein A/G

Immunogen: Recombinant human FTL protein fragment (around aa 38-165) (exact sequence is proprietary)

Klon: FTL-2338R

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

Positive Control: HepG2, HeLa, HL-60 or 293T cells. Pancreas, Liver, Cerebellum or Testis.

Known Application: Western Blot (0.5-2 μg/mL),Immunohistochemistry (Formalin-fixed) (0.5-1.0 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-80 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu FTL

Target: FTL (Ferritin, Light Polypeptide (FTL))

Andere Bezeichnung: FTL (FTL Produkte)

Synonyme: NBIA3 antikoerper, apoferritin antikoerper, ferritin antikoerper, fhc antikoerper, fth antikoerper, fth1 antikoerper, fthl6 antikoerper, ftn-2 antikoerper, pig15 antikoerper, plif antikoerper, FT antikoerper, Ftl antikoerper, Ftl-1 antikoerper, L-ferritin antikoerper, FTL antikoerper, Ftl1 antikoerper, FTL2 antikoerper, FTD antikoerper, ferritin light chain antikoerper, ferritin, heavy polypeptide 1 L homeolog antikoerper, ferritin light polypeptide 1 antikoerper, ferritin, light polypeptide antikoerper, ferritin light-chain antikoerper, ferritin light chain 1 antikoerper, FTL antikoerper, fth1.L antikoerper, Ftl1 antikoerper, CpipJ_CPIJ004069 antikoerper, Ftl antikoerper

Hintergrund: Mammalian ferritins consist of 24 subunits made up of 2 types of polypeptide chains, ferritin heavy chain and ferritin light chain. Ferritin heavy chains catalyze the first step in iron storage, the oxidation of Fe (II), whereas ferritin light chains promote the nucleation of ferrihydrite, enabling storage of Fe (III). Light chain ferritin is involved in cataracts by at least two mechanisms, hereditary hyperferritinemia cataract syndrome, in which light chain ferritin is overexpressed, and oxidative stress, an important factor in the development of ageing-related cataracts.

Molekulargewicht: 19-25kDa

Gen-ID: 2512

UniProt: P02792

Pathways: Transition Metal Ion Homeostasis