NKX2-8 Antikörper (AA 10-123)

Produktnummer ABIN6939492

Produktdetails anti-NKX2-8 Antikörper

Target: NKX2-8 (NK2 Homeobox 8 (NKX2-8))

Bindungsspezifität: AA 10-123

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser NKX2-8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Aufreinigung: Purified by Protein A/G

Immunogen: Human recombinant NKX2.8 protein fragment (around aa 10-123) (exact sequence is proprietary)

Klon: NKX28-2547

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise:

Positive Control: Human Liver, Kidney or Thyroid tissue (IHC).

Known Application: Western Blot (0.5 μg-1 μg/mL), Optimal dilution for a specific application should be determined.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-80 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu NKX2-8

Target: NKX2-8 (NK2 Homeobox 8 (NKX2-8))

Andere Bezeichnung: NKX2-8 (NKX2-8 Produkte)

Synonyme: NKX2.8 antikoerper, NKX2H antikoerper, Nkx2-9 antikoerper, Nkx-2.9 antikoerper, Nkx2-8 antikoerper, Nkx2.9 antikoerper, tinman antikoerper, NK2 homeobox 8 antikoerper, NK2 homeobox 9 antikoerper, NKX2-8 antikoerper, Nkx2-9 antikoerper, Nkx2-8 antikoerper

Hintergrund: The protein encoded by this gene is a homeobox-containing developmental regulator associated with liver development. The encoded protein binds to the alpha-fetoprotein (AFP) gene promoter and increases the expression of AFP. This gene is overexpressed in some lung cancers and is linked to poor patient survival, possibly due to its resistance to cisplatin. This gene is aberrantly methylated in pancreatic cancer, deleted in squamous cell lung carcinomas, and acts as a tumor suppressor in esophageal cancer. Mutations in this gene may also be a cause of neural tube defects.

Molekulargewicht: 26kDa

Gen-ID: 26257

UniProt: O15522