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GP2 Antikörper (AA 35-179)

GP2 Reaktivität: Human IHC, ELISA, Coat, StM Wirt: Maus Monoclonal GP2-1805 unconjugated
Produktnummer ABIN6939544
  • Target Alle GP2 Produkte
    GP2 (Glycoprotein 2 (Zymogen Granule Membrane) (GP2))
    Bindungsspezifität
    • 27
    • 8
    • 7
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 35-179
    Reaktivität
    • 47
    • 8
    • 4
    • 2
    • 2
    • 1
    Human
    Wirt
    • 32
    • 24
    Maus
    Klonalität
    • 28
    • 28
    Monoklonal
    Konjugat
    • 28
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser GP2 Antikörper ist unkonjugiert
    Applikation
    • 33
    • 31
    • 23
    • 19
    • 19
    • 12
    • 9
    • 7
    • 3
    • 3
    • 2
    • 2
    • 1
    Immunohistochemistry (IHC), ELISA, Coating (Coat), Staining Methods (StM)
    Aufreinigung
    Purified by Protein A/G
    Immunogen
    Recombinant fragment of human GP2 protein (around aa 35-179) (exact sequence is proprietary)
    Klon
    GP2-1805
    Isotyp
    IgG2c kappa
  • Applikationshinweise

    Positive Control: PANC-1 cells. Pancreas.

    Known Application: ELISA (Use Ab at 2-4 μg/mL for coating) (Order Ab without BSA), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    200 μg/mL
    Buffer
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-80 °C
    Informationen zur Lagerung
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    Haltbarkeit
    24 months
  • Target
    GP2 (Glycoprotein 2 (Zymogen Granule Membrane) (GP2))
    Andere Bezeichnung
    GP2 (GP2 Produkte)
    Synonyme
    ZAP75 antikoerper, 2310037I18Rik antikoerper, AV060639 antikoerper, gp80 antikoerper, glycoprotein 2 antikoerper, glycoprotein 2 (zymogen granule membrane) antikoerper, GP2 antikoerper, Gp2 antikoerper
    Substanzklasse
    Viral Protein
    Hintergrund
    GP2 (glycoprotein 2), also known as ZAP75, is a 537 amino acid secreted protein. It is an integral membrane protein that is secreted from intracellular zymogen granules and associates with the plasma membrane via glycosylphosphatidylinositol (GPI) linkage. GP2 is cleaved and then released into the pancreatic duct along with exocrine secretions. GP2 binds pathogens such as enterobacteria, thereby playing an important role in the innate immune response. The C-terminus of this protein is related to the C-terminus of the protein encoded by the neighboring gene, uromodulin (UMOD). GP2 is also expressed on the apical plasma membrane of specialized microfold (M) cells among enterocytes and serves as a transcytotic receptor for mucosal antigens. M cells are considered a promising target for oral vaccination against various infectious diseases.
    Molekulargewicht
    59kDa
    Gen-ID
    2813
    UniProt
    P55259
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