CD235a/GYPA Antikörper

Produktnummer ABIN6939585

Produktdetails anti-CD235a/GYPA Antikörper

Target: CD235a/GYPA (GYPA) (Glycophorin A (GYPA))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD235a/GYPA Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunofluorescence (IF), Staining Methods (StM)

Spezifität: Recognizes a sialoglycoprotein of 39 kDa, identified as glycophorin A (GPA). It is present on red blood cells (RBC) and erythroid precursor cells. It has been shown that glycophorin acts as the receptor for Sandei virus and parvovirus. Glycophorins A (GPA) and B (GPB), which are single, trans-membrane sialoglycoproteins. GPA is the carrier of blood group M and N specificities, while GPB accounts for S and U specificities. GPA and GPB provide the cells with a large mucin like surface and it has been suggested this provides a barrier to cell fusion, so minimizing aggregation between red blood cells in the circulation.

Aufreinigung: Purified by Protein A/G

Immunogen: Formalin fixed membrane from a Hairy cell leukemia

Klon: JC159

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise:

Positive Control: Erythrocytes in any human tissues.

Known Application: Flow Cytometry (0.5-1 μg/million cells), Immunofluorescence (0.5-1 μg/mL), ,Immunohistochemistry (Formalin-fixed) (0.25-0.5 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-80 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu CD235a/GYPA

Target: CD235a/GYPA (GYPA) (Glycophorin A (GYPA))

Andere Bezeichnung: GYPA (GYPA Produkte)

Synonyme: GYPA antikoerper, gpa antikoerper, AI853584 antikoerper, CD235a antikoerper, GPA antikoerper, GPErik antikoerper, GPSAT antikoerper, HGpMiV antikoerper, HGpMiXI antikoerper, HGpSta(C) antikoerper, MN antikoerper, MNS antikoerper, PAS-2 antikoerper, glycophorin A (MNS blood group) antikoerper, glycophorin A antikoerper, GYPA antikoerper, Gypa antikoerper

Molekulargewicht: 39kDa

Gen-ID: 2993, 2994

UniProt: P02724

Pathways: Maintenance of Protein Location