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ICAM-3/CD50 Antikörper

ICAM3 Reaktivität: Human FACS, IF, Bind Wirt: Maus Monoclonal CG106 unconjugated
Produktnummer ABIN6939686
  • Target Alle ICAM-3/CD50 (ICAM3) Antikörper anzeigen
    ICAM-3/CD50 (ICAM3) (Intercellular Adhesion Molecule 3 (ICAM3))
    Reaktivität
    • 111
    • 3
    • 2
    • 2
    Human
    Wirt
    • 67
    • 43
    • 1
    Maus
    Klonalität
    • 71
    • 40
    Monoklonal
    Konjugat
    • 59
    • 10
    • 6
    • 6
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser ICAM-3/CD50 Antikörper ist unkonjugiert
    Applikation
    • 60
    • 48
    • 44
    • 34
    • 26
    • 24
    • 21
    • 13
    • 7
    • 6
    • 6
    • 6
    • 5
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Immunofluorescence (IF), Binding Studies (Bind)
    Spezifität
    Recognizes the D1 domain of an N-glycosylated glycoprotein of 120 kDa with intra-chain disulfide bonds, identified as CD50 or ICAM-3 (Leucocyte Workshop VI). CD50 is the major ligand for LFA-1 (CD11a/CD18) and may have signaling role to increase adhesion. It is expressed on thymocytes and T lymphocytes and is resistant to treatment with phosphatidylinositol (PI) phospholipase C. This MAb is excellent for staining of formalin/paraffin tissues.
    Aufreinigung
    Purified by Protein A/G
    Immunogen
    Stimulated human leukocytes
    Klon
    CG106
    Isotyp
    IgG2a kappa
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  • Applikationshinweise

    Positive Control: HL-60 or THP-1 cells. Lymph node and tonsil.

    Known Application: Blocks binding of CD11a (LFA-1) to CD50 (ICAM-3) (Order Ab without Azide), Flow Cytometry (0.5-1 μg/million cells), Immunofluorescence (0.5-1 μg/mL), Optimal dilution for a specific application should be determined.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    200 μg/mL
    Buffer
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-80 °C
    Informationen zur Lagerung
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    Haltbarkeit
    24 months
  • Target
    ICAM-3/CD50 (ICAM3) (Intercellular Adhesion Molecule 3 (ICAM3))
    Andere Bezeichnung
    ICAM3 (ICAM3 Produkte)
    Synonyme
    CD50 antikoerper, CDW50 antikoerper, ICAM-R antikoerper, ICAM-3 antikoerper, ICAM3 antikoerper, intercellular adhesion molecule 3 antikoerper, ICAM3 antikoerper, Icam3 antikoerper
    Molekulargewicht
    110-160kDa
    Gen-ID
    3385
    UniProt
    P32942
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