IFNA1 Antikörper

Produktnummer ABIN6939689

Produktdetails anti-IFNA1 Antikörper

Target: IFNA1 (Interferon, alpha 1 (IFNA1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser IFNA1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))

Aufreinigung: Purified by Protein A/G

Immunogen: Purified recombinant human IFN-alpha1

Klon: Feb-48

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise:

Positive Control: Stimulated human peripheral blood mononuclear cells.

Known Application: Flow Cytometry (0.5-1 μg/million cells), Western Blot (1-2 μg/mL), Immunohistochemistry (frozen), Immunofluorescence (0.5-1 μg/mL), Optimal dilution for a specific application should be determined.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-80 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu IFNA1

Target: IFNA1 (Interferon, alpha 1 (IFNA1))

Andere Bezeichnung: IFNA1 (IFNA1 Produkte)

Synonyme: IFL antikoerper, IFN antikoerper, IFN-ALPHA antikoerper, IFN-alphaD antikoerper, IFNA13 antikoerper, IFNA@ antikoerper, Ifa1 antikoerper, IFN-ALPHA-1 antikoerper, IFN1@ antikoerper, IFNA1 antikoerper, IFN-alpha antikoerper, IFN-gamma antikoerper, IFNA antikoerper, IFNA2 antikoerper, IFNA6 antikoerper, IFN-alpha1 antikoerper, interferon alpha 13 antikoerper, interferon alpha 1 antikoerper, interferon, alpha 1 antikoerper, interferon, alpha 13 antikoerper, interferon antikoerper, interferon-alpha 1 antikoerper, interferon, alpha, leukocyte antikoerper, interferon-alpha-14 antikoerper, IFNA13 antikoerper, IFNA1 antikoerper, Ifna1 antikoerper, ifna1 antikoerper, IFNA3 antikoerper, IFN-ALPHA-14 antikoerper

Hintergrund: This MAb is specific for human interferon alpha 1 and does not cross react with human interferon alpha 2. Interferons are widely used therapeutic agents because of their anti-tumor and anti-viral effects and because of their modulatory effects on the immune system. These cytokines produce their effects by binding to the Type 1 Interferon- Receptor (IFNAR1). Down regulation of this receptor plays a key role in determining the magnitude and duration of cytokine signaling. This down regulation is influenced by phosphorylation of Serine 535 and 539 in the IFNAR1.

Molekulargewicht: 16-27kDa

Gen-ID: 3439

UniProt: P01562

Pathways: JAK-STAT Signalweg, Hepatitis C