Rekombinanter IGF1 Antikörper
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- Target Alle IGF1 Antikörper anzeigen
- IGF1 (Insulin-Like Growth Factor 1 (IGF1))
- Antikörpertyp
- Recombinant Antibody
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Reaktivität
- Human, Maus, Ratte, Kaninchen
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Wirt
- Kaninchen
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Klonalität
- Monoklonal
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Konjugat
- Dieser IGF1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS), Coating (Coat)
- Spezifität
- This antibody is specific to Insulin-like Growth Factor (IGF-1) and shows minimal cross-reaction with IGF-11, Proinsulin, MSF, and Insulin. IGF-1 is a polypeptide growth factor with two isoforms that are produced by alternative splicing. Isoform 1 is also known as IGF-IB while isoform 2 is known as IGF-IA. IGF-1 stimulates the proliferation of a wide range of cell types including muscle, bone and cartilage tissue. It functions as an autocrine regulator of growth. Activation of IGF system has emerged as a key factor for tumor progression and resistance to apoptosis in many cancers like those of breast, thyroid and colon.
- Aufreinigung
- Purified by Protein A/G
- Immunogen
- Recombinant full-length human IGF-1 protein
- Klon
- IGF1-2872R
- Isotyp
- IgG
- Top Product
- Discover our top product IGF1 Primärantikörper
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- Applikationshinweise
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Positive Control: Breast, Thyroid or Colon Cancers (IHC). K562 cells (FACS). IGF-1 recombinant protein (WB).
Known Application: ELISA (For coating, order antibody without BSA), Flow Cytometry (1-2 μg/million cells), Immunofluorescence (0.5-1 μg/mL), Optimal dilution for a specific application should be determined.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 200 μg/mL
- Buffer
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-80 °C
- Informationen zur Lagerung
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Haltbarkeit
- 24 months
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- Target
- IGF1 (Insulin-Like Growth Factor 1 (IGF1))
- Andere Bezeichnung
- IGF1 (IGF1 Produkte)
- Synonyme
- IGF-I antikoerper, IGF1A antikoerper, IGFI antikoerper, C730016P09Rik antikoerper, Igf-1 antikoerper, Igf-I antikoerper, Npt2B antikoerper, IGF-1 antikoerper, IGFIA antikoerper, IGF-IB antikoerper, igf1 antikoerper, IGF-1L antikoerper, IGF-1a antikoerper, IGF1 antikoerper, igf-1 antikoerper, igf1-A antikoerper, igf1.S antikoerper, xigf1 antikoerper, insulin like growth factor 1 antikoerper, insulin-like growth factor 1 antikoerper, insulin-like growth factor I antikoerper, insulin like growth factor 1 L homeolog antikoerper, IGF1 antikoerper, Igf1 antikoerper, LOC100136741 antikoerper, igf1 antikoerper, LOC678666 antikoerper, igf1.L antikoerper, LOC104911603 antikoerper
- Molekulargewicht
- ~7.6kDa
- Gen-ID
- 3479
- UniProt
- P05019
- Pathways
- RTK Signalweg, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Hormone Activity, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Stem Cell Maintenance, Glycosaminoglycan Metabolic Process, Regulation of Carbohydrate Metabolic Process, Autophagie, Smooth Muscle Cell Migration, Activated T Cell Proliferation, Positive Regulation of fat Cell Differentiation
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