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Rekombinanter IGKC Antikörper

IGKC Reaktivität: Human IHC, StM Wirt: Kaninchen Monoclonal KLC2289R unconjugated Recombinant Antibody
Produktnummer ABIN6939753
  • Target Alle IGKC Produkte
    IGKC (Immunoglobulin kappa Constant (IGKC))
    Antikörpertyp
    Recombinant Antibody
    Reaktivität
    Human
    Wirt
    • 10
    • 8
    Kaninchen
    Klonalität
    • 11
    • 7
    Monoklonal
    Konjugat
    • 13
    • 2
    • 1
    • 1
    • 1
    Dieser IGKC Antikörper ist unkonjugiert
    Applikation
    • 7
    • 6
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    Immunohistochemistry (IHC), Staining Methods (StM)
    Spezifität
    This MAb is specific to kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. It recognizes human Ig kappa light chains of both secreted and cell surface immunoglobulin. It detects also free kappa light chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.
    Aufreinigung
    Purified by Protein A/G
    Immunogen
    Recombinant full-length human Ig kappa chain (IGKC) protein
    Klon
    KLC2289R
    Isotyp
    IgG
  • Applikationshinweise

    Positive Control: 293T, Raji or hPBL cells. Tonsil or Spleen.

    Known Application: Immunohistochemistry (Formalin-fixed) (0.5-1.0 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    200 μg/mL
    Buffer
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-80 °C
    Informationen zur Lagerung
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    Haltbarkeit
    24 months
  • Target
    IGKC (Immunoglobulin kappa Constant (IGKC))
    Andere Bezeichnung
    IGKC (IGKC Produkte)
    Synonyme
    HCAK1 antikoerper, IGKCD antikoerper, Km antikoerper, IGKC antikoerper, Igk-C antikoerper, immunoglobulin kappa constant antikoerper, immunoglobulin kappa constant L homeolog antikoerper, IGKC antikoerper, LOC708048 antikoerper, igkc antikoerper, igkc.L antikoerper, Igkc antikoerper
    Molekulargewicht
    ~22.5kDa
    Gen-ID
    3514
    UniProt
    P01601, P01834
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