Rekombinanter Integrin beta 3 Antikörper (AA 385-490)
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- Target Alle Integrin beta 3 (ITGB3) Antikörper anzeigen
- Integrin beta 3 (ITGB3)
- Antikörpertyp
- Recombinant Antibody
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Bindungsspezifität
- AA 385-490
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Monoklonal
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Konjugat
- Dieser Integrin beta 3 Antikörper ist unkonjugiert
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Applikation
- Immunohistochemistry (IHC), Staining Methods (StM)
- Spezifität
- Reacts with human integrin beta3 (GPIIIa, vitronectin receptor beta chain). It associates with the IIb-chain (CD41) to form the GpIIb/GpIIIa complex (CD41/CD61).The CD41/CD61 complex appears early in megakaryocyte maturation. The activated CD41/CD61 complex is a receptor for von Willebrand factor, soluble fibrinogen, fibronectin, vitronectin and thrombospondin. It plays a central role in platelet activation and aggregation. The CD51/CD61 is implicated in tumor metastasis and adenoviral infection. The antibody detects platelets in smears of blood and bone marrow, as well as megakaryocytes in frozen sections and cell smears. The antibody is useful for classification of megakaryoblastic leukemia.
- Aufreinigung
- Purified by Protein A/G
- Immunogen
- Recombinant human ITGB3 protein fragment (aa 385-490) (exact sequence is proprietary)
- Klon
- ITGB3-2166R
- Isotyp
- IgG
- Top Product
- Discover our top product ITGB3 Primärantikörper
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anti-Integrin beta 3 (ITGB3) (AA 134-376) antibody
ITGB3 Reaktivität: Maus WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Integrin beta 3 (ITGB3) (AA 27-120) antibodyITGB3 Reaktivität: Human, Maus WB, FACS, ELISA, IHC (fro), IHC (p), IF (cc), IF (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Integrin beta 3 (ITGB3) (AA 27-179) antibodyITGB3 Reaktivität: Human FACS, IHC, ELISA Wirt: Maus Monoclonal 3E8A6 unconjugated
anti-Integrin beta 3 (ITGB3) antibodyITGB3 Reaktivität: Human WB, IHC, IP Wirt: Kaninchen Monoclonal unconjugated
anti-Integrin beta 3 (ITGB3) antibody (FITC)ITGB3 Reaktivität: Human, Non-Human Primate FACS Wirt: Maus Monoclonal VIPL2 FITC
anti-Integrin beta 3 (ITGB3) antibody (PerCP)ITGB3 Reaktivität: Human, Non-Human Primate FACS Wirt: Maus Monoclonal VIPL2 PerCP
anti-Integrin beta 3 (ITGB3) (AA 385-490) antibodyITGB3 Reaktivität: Human IHC, StM Wirt: Maus Monoclonal ITGB3-2145 unconjugated
anti-Integrin beta 3 (ITGB3) (AA 610-718) antibodyITGB3 Reaktivität: Human WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Integrin beta 3 (ITGB3) (AA 734-760) antibodyITGB3 Reaktivität: Human WB, FACS, IHC, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-Integrin beta 3 (ITGB3) antibodyITGB3 Reaktivität: Human, Non-Human Primate WB, FACS, IHC (fro) Wirt: Maus Monoclonal VIPL2 unconjugated
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- Applikationshinweise
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Positive Control: U937, KG1a, HEL cells. Spleen.
Known Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 10-20 min followed by cooling at RT for 20 minutes) Optimal dilution for a specific application should be determined.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 200 μg/mL
- Buffer
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-80 °C
- Informationen zur Lagerung
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Haltbarkeit
- 24 months
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- Target
- Integrin beta 3 (ITGB3)
- Andere Bezeichnung
- ITGB3 (ITGB3 Produkte)
- Molekulargewicht
- 105kDa & 90kDa
- Gen-ID
- 3690
- UniProt
- P05106
- Pathways
- Regulation of G-Protein Coupled Receptor Protein Signaling, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Integrin Complex
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