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Cytokeratin 5 Antikörper (AA 316-590)

KRT5 Reaktivität: Human IHC, StM Wirt: Maus Monoclonal KRT5-3594 unconjugated
Produktnummer ABIN6939864
  • Target Alle Cytokeratin 5 (KRT5) Antikörper anzeigen
    Cytokeratin 5 (KRT5) (Keratin 5 (KRT5))
    Bindungsspezifität
    • 16
    • 16
    • 11
    • 8
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 316-590
    Reaktivität
    • 128
    • 78
    • 53
    • 10
    • 10
    • 10
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 92
    • 43
    • 2
    Maus
    Klonalität
    • 83
    • 54
    Monoklonal
    Konjugat
    • 60
    • 13
    • 10
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Dieser Cytokeratin 5 Antikörper ist unkonjugiert
    Applikation
    • 87
    • 48
    • 46
    • 29
    • 24
    • 19
    • 15
    • 14
    • 13
    • 9
    • 6
    • 6
    • 5
    • 5
    • 2
    • 2
    • 1
    Immunohistochemistry (IHC), Staining Methods (StM)
    Spezifität
    This MAb recognizes a protein of 58 kDa, which is identified as Cytokeratin 5 (KRT5). This type II cytokeratin is specifically expressed in the basal layer of the epidermis with family member KRT14. Antibodies to KRT5 identify basal cells of squamous and glandular epithelia, myoepithelia, and mesothelium.Anti-cytokeratin 5 has been reported useful in the differential diagnosis of metastatic carcinoma in the pleura versus epithelioid mesothelioma. Almost all squamous cell carcinomas, half of transitional carcinomas, and many undifferentiated large cell carcinomas express.Anti-KRT5, along with anti-p63, affords a high sensitivity and specificity for squamous differentiation. Myoepithelial cells of the breast, glandular epithelia, and basal cells of the prostate are labeled with anti-KRT5.
    Aufreinigung
    Purified by Protein A/G
    Immunogen
    Recombinant fragment (around aa 316-590) of human Cytokeratin 5 (KRT5) protein (exact sequence is proprietary)
    Klon
    KRT5-3594
    Isotyp
    IgG1 kappa
    Top Product
    Discover our top product KRT5 Primärantikörper
  • Applikationshinweise

    Positive Control: MCF-7 or HeLa cells. Human tonsil, esophagus or bladder tissue (IHC).

    Known Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    200 μg/mL
    Buffer
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-80 °C
    Informationen zur Lagerung
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    Haltbarkeit
    24 months
  • Target
    Cytokeratin 5 (KRT5) (Keratin 5 (KRT5))
    Andere Bezeichnung
    KRT5 (KRT5 Produkte)
    Synonyme
    3300001P10Rik antikoerper, AW146334 antikoerper, CK5 antikoerper, K5 antikoerper, Krt2-5 antikoerper, Tfip8 antikoerper, DDD antikoerper, DDD1 antikoerper, EBS2 antikoerper, KRT5A antikoerper, Sak57 antikoerper, ckii antikoerper, wu:fb02h09 antikoerper, wu:fj02d02 antikoerper, wu:fk78b12 antikoerper, zfCKII antikoerper, KRT75 antikoerper, CK-5 antikoerper, Keratin-5 antikoerper, keratin 5 antikoerper, Krt5 antikoerper, KRT5 antikoerper, krt5 antikoerper
    Molekulargewicht
    58kDa
    Gen-ID
    3852
    UniProt
    P13647
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