Rekombinanter KRT6A Antikörper

Produktnummer ABIN6939868

Produktdetails anti-KRT6A Antikörper

Target: KRT6A (Keratin 6A (KRT6A))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser KRT6A Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Staining Methods (StM)

Spezifität: This MAb recognizes a protein of 56 kDa, identified as cytokeratin 6A (KRT6A). In humans, multiple isoforms of Cytokeratin 6 (6A-6F), encoded by several highly homologous genes, have distinct tissue expression patterns. Cytokeratin 6A is the dominant form in epithelial tissue. Cytokeratin 6 and 16 are expressed in keratinocytes, which are undergoing rapid turnover in the suprabasal region (also known as hyper-proliferation-related keratins). Cytokeratin 6 is found in hair follicles, suprabasal cells of a variety of internal stratified epithelia, in epidermis, in both normal and hyper-proliferative situations. Epidermal injury results in activation of keratinocytes, which express KRT6 and KRT16. KRT6 is strongly expressed in about 75 % of head and neck squamous cell carcinomas.

Aufreinigung: Purified by Protein A/G

Immunogen: Recombinant full-length human Cytokeratin 6A (KRT6A) protein

Klon: RKRT6A-2100

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise:

Positive Control: Tonsil or basal cell carcinoma.

Known Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-80 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu KRT6A

Target: KRT6A (Keratin 6A (KRT6A))

Andere Bezeichnung: KRT6A (KRT6A Produkte)

Synonyme: CK6A antikoerper, CK6C antikoerper, CK6D antikoerper, K6A antikoerper, K6C antikoerper, K6D antikoerper, KRT6C antikoerper, KRT6D antikoerper, 2310016L08Rik antikoerper, Krt2-6a antikoerper, Krt2-6c antikoerper, MK6a antikoerper, mK6[a] antikoerper, CK-6A antikoerper, Krt6a antikoerper, KRT6A antikoerper, keratin 6A antikoerper, similar to keratin complex 2, basic, gene 6a antikoerper, keratin, type II cytoskeletal 6A antikoerper, KRT6A antikoerper, Krt6a antikoerper, LOC683313 antikoerper, LOC101112304 antikoerper

Molekulargewicht: 58kDa

Gen-ID: 3853

UniProt: P02538