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Rekombinanter Keratin 10 Antikörper

KRT10 Reaktivität: Human, Hund, Cat IHC, StM Wirt: Kaninchen Monoclonal KRT10-1948R unconjugated Recombinant Antibody
Produktnummer ABIN6939904
  • Target Alle Keratin 10 (KRT10) Antikörper anzeigen
    Keratin 10 (KRT10)
    Antikörpertyp
    Recombinant Antibody
    Reaktivität
    • 123
    • 56
    • 53
    • 27
    • 17
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human, Hund, Cat
    Wirt
    • 77
    • 48
    • 2
    Kaninchen
    Klonalität
    • 66
    • 61
    Monoklonal
    Konjugat
    • 65
    • 10
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Keratin 10 Antikörper ist unkonjugiert
    Applikation
    • 74
    • 55
    • 51
    • 38
    • 35
    • 22
    • 14
    • 13
    • 11
    • 11
    • 11
    • 7
    • 3
    • 2
    • 2
    • 1
    Immunohistochemistry (IHC), Staining Methods (StM)
    Spezifität
    This MAb recognizes a protein of 56.5 kDa, identified as cytokeratin 10 (CK10). CK10 is expressed in all suprabasal layers of the epidermis. In the epidermis, expression of CK10 strictly parallels the extent of differentiation, it is absent in the basal layer, appears in the first suprabasal layers and increases in concentration towards the granular layer. However, CK10 is rarely detected in early stages of vulvar squamous carcinomas (tumors less than 2 cm, clinical stage I) regardless of the tumor grade. In larger and more advanced tumors (greater than 2 cm, clinical stages II and III), CK10 is detected very frequently. Expression of CK10 is related to maturation of malignant keratinocytes, being preferentially detected in more-differentiated parts.
    Aufreinigung
    Purified by Protein A/G
    Immunogen
    Recombinant human full-length KRT10 protein
    Klon
    KRT10-1948R
    Isotyp
    IgG
    Top Product
    Discover our top product KRT10 Primärantikörper
  • Applikationshinweise

    Positive Control: A431, HeLa, MCF7 cells. Esophagus or tonsil.

    Known Application: Immunohistochemistry (Formalin-fixed) (0.1-0.2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    200 μg/mL
    Buffer
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-80 °C
    Informationen zur Lagerung
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    Haltbarkeit
    24 months
  • Target
    Keratin 10 (KRT10)
    Andere Bezeichnung
    KRT10 (KRT10 Produkte)
    Synonyme
    BCIE antikoerper, BIE antikoerper, CK10 antikoerper, EHK antikoerper, K10 antikoerper, KPP antikoerper, D130054E02Rik antikoerper, K1C1 antikoerper, Krt-1.10 antikoerper, Krt1-10 antikoerper, Ka10 antikoerper, Ker10 antikoerper, KRT10 antikoerper, KRT25 antikoerper, KRT27 antikoerper, KRT28 antikoerper, keratin 10 antikoerper, keratin 10, type I S homeolog antikoerper, keratin, type I cytoskeletal 25 antikoerper, KRT10 antikoerper, Krt10 antikoerper, krt10.S antikoerper, LOC101085587 antikoerper
    Molekulargewicht
    56.5kDa
    Gen-ID
    3858
    UniProt
    P13645
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