Rekombinanter LGALS1/Galectin 1 Antikörper (AA 12-108)

Produktnummer ABIN6939959

Produktdetails anti-LGALS1/Galectin 1 Antikörper

Target: LGALS1/Galectin 1 (LGALS1) (Lectin, Galactoside-Binding, Soluble, 1 (LGALS1))

Antikörpertyp: Recombinant Antibody

Bindungsspezifität: AA 12-108

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser LGALS1/Galectin 1 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC), Coating (Coat), Staining Methods (StM)

Aufreinigung: Purified by Protein A/G

Immunogen: Recombinant fragment (around aa 12-108) of human Galectin-1 protein (exact sequence is proprietary)

Klon: GAL1-2499R

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

Positive Control: HeLa, K562 or 293 cells. Prostate, Kidney, Placenta, Stomach, Skin, Spleen, Brain or Heart.

Known Application: ELISA (Use Ab at 2-4 μg/mL for coating) (Order Ab without BSA), Immunohistochemistry (Formalin-fixed) (0.5-1 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-80 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu LGALS1/Galectin 1

Target: LGALS1/Galectin 1 (LGALS1) (Lectin, Galactoside-Binding, Soluble, 1 (LGALS1))

Andere Bezeichnung: LGALS1 (LGALS1 Produkte)

Synonyme: GAL1 antikoerper, GBP antikoerper, Galectin-1 antikoerper, LGAS1 antikoerper, LGALS1 antikoerper, MGC64502 antikoerper, GB10026 antikoerper, AA410090 antikoerper, Gal-1 antikoerper, Galbp antikoerper, L-14.5 antikoerper, L14 antikoerper, Lect14 antikoerper, galectin-1 antikoerper, Galaptin antikoerper, galectin 1 antikoerper, galectin-1 antikoerper, lectin, galactoside-binding, soluble, 1 L homeolog antikoerper, protein enabled antikoerper, lectin, galactose binding, soluble 1 antikoerper, LGALS1 antikoerper, Lgals1 antikoerper, CC1G_05003 antikoerper, CC1G_05004 antikoerper, lgals1.L antikoerper, LOC408848 antikoerper

Hintergrund: Galectin-1 is a member of the beta-galactoside-binding family and is a dimeric protein of 14kD participating in a variety of normal and pathological processes, including cancer progression. Galectin-1 can affect the proliferation of normal and malignant cells. Inhibition of cell growth is observed in a lactose-dependent manner as lower concentrations of the lectin stimulate cell proliferation. Galectin-1 may also be implicated in the induction of apoptosis of activated T cells through the binding of exogenous galectin-1 to CD45 Molecules present on the surface of lymphocytes. Galectin-1, reported to be present either at the surface of cancer cells or accumulated around these cells could act as an immunological shield to protect against a T cell immune response and provide an advantage for survival.

Molekulargewicht: 14kDa

Gen-ID: 3956

UniProt: P09382

Pathways: Carbohydrate Homeostasis