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LHCGR Antikörper (AA 70-410)

LHCGR Reaktivität: Human WB, IF, FACS Wirt: Maus Monoclonal LHCGR-1416 unconjugated
Produktnummer ABIN6939963
  • Target Alle LHCGR Antikörper anzeigen
    LHCGR (Luteinizing Hormone/Choriogonadotropin Receptor (LHCGR))
    Bindungsspezifität
    • 23
    • 15
    • 6
    • 6
    • 5
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 70-410
    Reaktivität
    • 78
    • 31
    • 29
    • 5
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 56
    • 26
    • 1
    Maus
    Klonalität
    • 57
    • 26
    Monoklonal
    Konjugat
    • 31
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser LHCGR Antikörper ist unkonjugiert
    Applikation
    • 49
    • 31
    • 27
    • 20
    • 14
    • 13
    • 13
    • 11
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)
    Spezifität
    Recognizes a protein of 78-85 kDa, which is identified as Luteinizing hormone / choriogonadotropin receptor. Luteinizing hormone plays a role in spermatogenesis and ovulation by stimulating the testes and ovaries to produce steroids. Choriogonadotropin production in the placenta maintains estrogen and progesterone levels during the first trimester of pregnancy. Ovaries and testes abundantly express luteinizing hormone / choriogonadotropin receptor (LHCGR) as a seven transmembrane, G protein-coupled receptor glycoprotein. LHCGR influences the protective effect of pregnancy and Gonadotropin against breast cancer. The expression of LHCGR on breast carcinoma correlates in part to the degree of tumor differentiation. LHCGR -positive breast tumors occur more frequently in tumors with greater cell differentiation in premenopausal women.
    Aufreinigung
    Purified by Protein A/G
    Immunogen
    Recombinant fragment (around aa 70-410) of human LHCGR protein (exact sequence is proprietary)
    Klon
    LHCGR-1416
    Isotyp
    IgG1 kappa
    Top Product
    Discover our top product LHCGR Primärantikörper
  • Applikationshinweise

    Positive Control: HepG2 or Jurkat cells. Ovary or Testis.

    Known Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Western Blot (1-2 μg/mL), Optimal dilution for a specific application should be determined.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    200 μg/mL
    Buffer
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-80 °C
    Informationen zur Lagerung
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    Haltbarkeit
    24 months
  • Target
    LHCGR (Luteinizing Hormone/Choriogonadotropin Receptor (LHCGR))
    Andere Bezeichnung
    LHCGR (LHCGR Produkte)
    Synonyme
    HHG antikoerper, LCGR antikoerper, LGR2 antikoerper, LH/CG-R antikoerper, LH/CGR antikoerper, LHR antikoerper, LHRHR antikoerper, LSH-R antikoerper, ULG5 antikoerper, Gpcr19-rs1 antikoerper, LH-R antikoerper, Lhr antikoerper, LSHR antikoerper, lhr antikoerper, GTHR-II antikoerper, zfGTHR-II antikoerper, LHCGR antikoerper, LOC100222883 antikoerper, lh-r antikoerper, LOC100305044 antikoerper, luteinizing hormone/choriogonadotropin receptor antikoerper, luteinizing hormone/choriogonadotropin receptor L homeolog antikoerper, luteinizing hormone receptor antikoerper, LHCGR antikoerper, Lhcgr antikoerper, lhcgr antikoerper, lhcgr.L antikoerper, lhr antikoerper, LOC100305044 antikoerper
    Molekulargewicht
    78-85kDa
    Gen-ID
    3973
    UniProt
    P22888
    Pathways
    Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, cAMP Metabolic Process, Glycosaminoglycan Metabolic Process, Regulation of Carbohydrate Metabolic Process, Autophagie, Negative Regulation of intrinsic apoptotic Signaling
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