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MMP2 Antikörper (AA 444-575)

MMP2 Reaktivität: Human WB Wirt: Maus Monoclonal MMP2-1501 unconjugated
Produktnummer ABIN6940067
  • Target Alle MMP2 Antikörper anzeigen
    MMP2 (Matrix Metalloproteinase 2 (MMP2))
    Bindungsspezifität
    • 16
    • 16
    • 16
    • 11
    • 10
    • 8
    • 6
    • 6
    • 6
    • 6
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 444-575
    Reaktivität
    • 149
    • 80
    • 66
    • 50
    • 7
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    Human
    Wirt
    • 124
    • 41
    Maus
    Klonalität
    • 123
    • 42
    Monoklonal
    Konjugat
    • 72
    • 14
    • 13
    • 12
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser MMP2 Antikörper ist unkonjugiert
    Applikation
    • 130
    • 55
    • 52
    • 39
    • 39
    • 33
    • 29
    • 25
    • 19
    • 14
    • 12
    • 4
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB)
    Spezifität
    It recognizes a protein of 72 kDa, which is identified as MMP2. The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, Fibronectin, Laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-2 (also designated type IV collagenase) cleaves collagen types IV,V, VII and X and gelatin type I. Activation of MMP-2 secretion requires the Ras signaling pathway.
    Aufreinigung
    Purified by Protein A/G
    Immunogen
    Recombinant human MMP2 protein fragment (aa 444-575) (exact sequence is proprietary)
    Klon
    MMP2-1501
    Isotyp
    IgG1 kappa
    Top Product
    Discover our top product MMP2 Primärantikörper
  • Applikationshinweise

    Positive Control: U-138 MG or U-87 MG cells. Placenta or Colon Carcinoma.

    Known Application: Western Blot (0.5-1 μg/mL) Optimal dilution for a specific application should be determined.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    200 μg/mL
    Buffer
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-80 °C
    Informationen zur Lagerung
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    Haltbarkeit
    24 months
  • Target
    MMP2 (Matrix Metalloproteinase 2 (MMP2))
    Andere Bezeichnung
    MMP2 (MMP2 Produkte)
    Synonyme
    2-MMP antikoerper, CG1794 antikoerper, DM2-MMP antikoerper, Dm2-MMP antikoerper, Dmel\\CG1794 antikoerper, MMP2 antikoerper, anon-WO0118547.84 antikoerper, dm-2MMP antikoerper, dmmp2 antikoerper, l(2)02353 antikoerper, mmp2 antikoerper, wu:fa99h12 antikoerper, wu:fk89d01 antikoerper, fgmmp-2 antikoerper, Mmp-2 antikoerper, LOC100135793 antikoerper, Clg4a antikoerper, GelA antikoerper, MMP-2 antikoerper, CLG4 antikoerper, CLG4A antikoerper, MMP-II antikoerper, MONA antikoerper, TBE-1 antikoerper, matrix metallopeptidase 2 antikoerper, Matrix metalloproteinase 2 antikoerper, matrix metalloproteinase 2 antikoerper, matrix metalloproteinase-2 antikoerper, MMP2 antikoerper, Mmp2 antikoerper, mmp2 antikoerper, LOC657982 antikoerper, LOC100135793 antikoerper
    Molekulargewicht
    72kDa (Pro), 63kDa (cleaved)
    Gen-ID
    4313
    UniProt
    P08253
    Pathways
    Activation of Innate immune Response
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