Moesin Antikörper

Produktnummer ABIN6940085

Produktdetails anti-Moesin Antikörper

Target: Moesin (MSN)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Moesin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS), Staining Methods (StM), Blocking Peptide (BP)

Spezifität: Recognizes 78 kDa moesin protein. Moesin, a member of the talin-4.1 superfamily, is a linking protein of the sub-membranous actin cytoskeleton. It is expressed in variable amounts in cells of different phenotypes such as macrophages, lymphocytes, fibroblastic, endothelial, epithelial, and neuronal cell lines but not in blood cells. The ERM proteins, ezrin, radixin, and moesin are involved in a variety of cellular functions, such as cell adhesion, migration, and the organization of cell surface structures, and are highly homologous, both in protein sequence and in functional activity, with merlin/schwannomin, a neurofibromatosis-2-associated tumor-suppressor protein. Cell lines of epithelial and mesothelial origin contain both moesin and radixin whereas cells of endothelial and lymphoid origin express moesin.

Keine Kreuzreaktivität: Ratte (Rattus)

Aufreinigung: Purified by Protein A/G

Immunogen: Recombinant full-length human Moesin protein

Klon: MSN-493

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise:

Positive Control: K562, HT-29, Jurkat, CH3LC or HUVEC cells. Uterus, placenta, tonsil (both B and T lymphocytes), skeletal muscle, thyroid or kidney.

Known Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (2-4 μg/mL), Western Blot (1-2 μg/mL), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-80 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu Moesin

Target: Moesin (MSN)

Andere Bezeichnung: MSN (MSN Produkte)

Synonyme: CG10701 antikoerper, D17 antikoerper, Dmel\\CG10701 antikoerper, Dmoe antikoerper, EMR1 antikoerper, ERM antikoerper, Emr1 antikoerper, anon-WO03040301.155 antikoerper, anon-WO03040301.157 antikoerper, anon-WO03040301.159 antikoerper, anon-WO03040301.161 antikoerper, dMoe antikoerper, gma antikoerper, l(1)G0067 antikoerper, l(1)G0323 antikoerper, l(1)G0404 antikoerper, l(1)G0415 antikoerper, moe antikoerper, moesin/ezrin/radixin homolog mRNA antikoerper, cb567 antikoerper, rdx antikoerper, wu:fb14b03 antikoerper, zgc:85640 antikoerper, MSN antikoerper, C78546 antikoerper, moesin antikoerper, Moesin antikoerper, moesin a antikoerper, moesin L homeolog antikoerper, MSN antikoerper, Moe antikoerper, msna antikoerper, msn.L antikoerper, moes antikoerper, Msn antikoerper

Molekulargewicht: 78kDa

Gen-ID: 4478

UniProt: P26038

Pathways: Asymmetric Protein Localization