MYCN Antikörper

Produktnummer ABIN6940152

Produktdetails anti-MYCN Antikörper

Target: MYCN (N-Myc Proto-Oncogene Protein (MYCN))

Reaktivität: Human, Maus, Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser MYCN Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Aufreinigung: Purified by Protein A/G

Immunogen: Recombinant full-length human n-Myc protein.

Klon: NMYC-1

Isotyp: IgG2a kappa

Anwendungsinformationen

Applikationshinweise:

Positive Control: 293T whole cell lysates or recombinant Human n-Myc protein.

Known Application: Immunofluorescence (0.5-1 μg/mL), Western Blot (0.5-1.0 μg/mL)Optimal dilution for a specific application should be determined.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-80 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu MYCN

Target: MYCN (N-Myc Proto-Oncogene Protein (MYCN))

Andere Bezeichnung: MYCN (MYCN Produkte)

Synonyme: MODED antikoerper, MYCNOT antikoerper, N-myc antikoerper, NMYC antikoerper, ODED antikoerper, bHLHe37 antikoerper, Nmyc antikoerper, Nmyc-1 antikoerper, Nmyc1 antikoerper, c-nmyc antikoerper, Nmuc1 antikoerper, fb57a02 antikoerper, nmyc1 antikoerper, wu:fb57a02 antikoerper, zgc:85706 antikoerper, XN-myc antikoerper, XNmyc antikoerper, mycn antikoerper, mycn-a antikoerper, mycn-b antikoerper, mycna antikoerper, xN-myc1 antikoerper, MYCN proto-oncogene, bHLH transcription factor antikoerper, v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog antikoerper, v-myc avian myelocytomatosis viral related oncogene, neuroblastoma derived antikoerper, olfactory receptor 8S1 antikoerper, MYCN proto-oncogene, bHLH transcription factor S homeolog antikoerper, MYCN antikoerper, Mycn antikoerper, LOC515887 antikoerper, mycn antikoerper, mycn.S antikoerper

Hintergrund: The v-Myc oncogene, initially identified in the MC29 avian retrovirus, causes myelocytomas, carcinomas, sarcomas and lymphomas, and belongs to a family of oncogenes conserved throughout evolution. In humans, the family consists of five genes: c-Myc, N-Myc, R-Myc, L-Myc and B-Myc. Amplification of the N-Myc gene has been found in human neuroblastomas and cell lines. Its amplification correlates well with the stage of neuroblastoma disease. Immunological studies have shown that the human N-Myc gene encodes a nuclear phosphoprotein that exhibits relatively short (30 min) half life in vivo. The prototype member of the family, c-Myc p67, binds DNA in a sequence-specific manner subsequent to dimerization with a second basic region helix-loop-helix leucine zipper motif protein, designated Max.

Molekulargewicht: 67kDa

Gen-ID: 4613

UniProt: P04198