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CD207 Antikörper (AA 74-213)

CD207 Reaktivität: Human WB, ELISA, Coat Wirt: Maus Monoclonal LGRN-1821 unconjugated
Produktnummer ABIN6940244
  • Target Alle CD207 Antikörper anzeigen
    CD207 (CD207 Molecule, Langerin (CD207))
    Bindungsspezifität
    • 12
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 74-213
    Reaktivität
    • 52
    • 38
    • 19
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 45
    • 16
    Maus
    Klonalität
    • 45
    • 16
    Monoklonal
    Konjugat
    • 28
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CD207 Antikörper ist unkonjugiert
    Applikation
    • 38
    • 18
    • 7
    • 7
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Coating (Coat)
    Aufreinigung
    Purified by Protein A/G
    Immunogen
    Recombinant fragment (around aa74-213) of human Langerin protein (exact sequence is proprietary)
    Klon
    LGRN-1821
    Isotyp
    IgG2a kappa
    Top Product
    Discover our top product CD207 Primärantikörper
  • Applikationshinweise

    Positive Control: HeLa or A549 cells (WB).

    Known Application: ELISA (Use Ab at 2-4 μg/mL for coating) (Order Ab without BSA), Western Blot (1-2 μg/mL)Optimal dilution for a specific application should be determined.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    200 μg/mL
    Buffer
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-80 °C
    Informationen zur Lagerung
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    Haltbarkeit
    24 months
  • Target
    CD207 (CD207 Molecule, Langerin (CD207))
    Andere Bezeichnung
    CD207 (CD207 Produkte)
    Hintergrund
    Langerhans cells (LCs) are a subset of immature dendritic cells (DCs) that specifically localize in the epidermis and other mucosal epithelia. Epidermal LCs possess strong immuno-stimulatory capacity and play a central role in the initiation and regulation of immune responses. Langerin (CD207) is a Ca2+-dependent, C-type lectin domain containing, type II transmembrane protein that induces epidermal LCs to differentiate into Birbeck granules (BG). BGs are organelles with superimposing and zippering membranes that influence proper class I type antigen presentation to the circulating T cells. Human spleen, lymph node, thymus, liver, lung and heart express Langerin protein.
    Molekulargewicht
    48kDa
    Gen-ID
    50489
    UniProt
    Q9UJ71
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