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CD207 Antikörper (AA 74-213)

CD207 Reaktivität: Human WB, ELISA, Coat Wirt: Maus Monoclonal LGRN-1821 unconjugated
Produktnummer ABIN6940244
  • Target Alle CD207 Antikörper anzeigen
    CD207 (CD207 Molecule, Langerin (CD207))
    Bindungsspezifität
    • 12
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 74-213
    Reaktivität
    • 52
    • 38
    • 19
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 45
    • 16
    Maus
    Klonalität
    • 45
    • 16
    Monoklonal
    Konjugat
    • 29
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CD207 Antikörper ist unkonjugiert
    Applikation
    • 39
    • 19
    • 8
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Coating (Coat)
    Aufreinigung
    Purified by Protein A/G
    Immunogen
    Recombinant fragment (around aa74-213) of human Langerin protein (exact sequence is proprietary)
    Klon
    LGRN-1821
    Isotyp
    IgG2a kappa
    Top Product
    Discover our top product CD207 Primärantikörper
  • Applikationshinweise

    Positive Control: HeLa or A549 cells (WB).

    Known Application: ELISA (Use Ab at 2-4 μg/mL for coating) (Order Ab without BSA), Western Blot (1-2 μg/mL)Optimal dilution for a specific application should be determined.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    200 μg/mL
    Buffer
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-80 °C
    Informationen zur Lagerung
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    Haltbarkeit
    24 months
  • Target
    CD207 (CD207 Molecule, Langerin (CD207))
    Andere Bezeichnung
    CD207 (CD207 Produkte)
    Synonyme
    CD207 antikoerper, CLEC4K antikoerper, RGD1565913 antikoerper, CD207 molecule antikoerper, CD207 antigen antikoerper, CD207 antikoerper, Cd207 antikoerper
    Hintergrund
    Langerhans cells (LCs) are a subset of immature dendritic cells (DCs) that specifically localize in the epidermis and other mucosal epithelia. Epidermal LCs possess strong immuno-stimulatory capacity and play a central role in the initiation and regulation of immune responses. Langerin (CD207) is a Ca2+-dependent, C-type lectin domain containing, type II transmembrane protein that induces epidermal LCs to differentiate into Birbeck granules (BG). BGs are organelles with superimposing and zippering membranes that influence proper class I type antigen presentation to the circulating T cells. Human spleen, lymph node, thymus, liver, lung and heart express Langerin protein.
    Molekulargewicht
    48kDa
    Gen-ID
    50489
    UniProt
    Q9UJ71
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