Rekombinanter CD207 Antikörper (AA 74-213)
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- Target Alle CD207 Antikörper anzeigen
- CD207 (CD207 Molecule, Langerin (CD207))
- Antikörpertyp
- Recombinant Antibody
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Bindungsspezifität
- AA 74-213
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Monoklonal
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Konjugat
- Dieser CD207 Antikörper ist unkonjugiert
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Applikation
- ELISA, Coating (Coat)
- Aufreinigung
- Purified by Protein A/G
- Immunogen
- Recombinant fragment (around aa74-213) of human Langerin protein (exact sequence is proprietary)
- Klon
- LGRN-3136R
- Isotyp
- IgG
- Top Product
- Discover our top product CD207 Primärantikörper
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- Applikationshinweise
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Positive Control: HeLa or A549 cells. Skin.
Known Application: ELISA (Use Ab at 2-4 μg/mL for coating) (Order Ab without BSA), Optimal dilution for a specific application should be determined.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 200 μg/mL
- Buffer
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-80 °C
- Informationen zur Lagerung
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Haltbarkeit
- 24 months
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- Target
- CD207 (CD207 Molecule, Langerin (CD207))
- Andere Bezeichnung
- CD207 (CD207 Produkte)
- Synonyme
- CD207 antikoerper, CLEC4K antikoerper, RGD1565913 antikoerper, CD207 molecule antikoerper, CD207 antigen antikoerper, CD207 antikoerper, Cd207 antikoerper
- Hintergrund
- Langerhans cells (LCs) are a subset of immature dendritic cells (DCs) that specifically localize in the epidermis and other mucosal epithelia. Epidermal LCs possess strong immuno-stimulatory capacity and play a central role in the initiation and regulation of immune responses. Langerin (CD207) is a Ca2+-dependent, C-type lectin domain containing, type II transmembrane protein that induces epidermal LCs to differentiate into Birbeck granules (BG). BGs are organelles with superimposing and zippering membranes that influence proper class I type antigen presentation to the circulating T cells. Human spleen, lymph node, thymus, liver, lung and heart express Langerin protein.
- Molekulargewicht
- 48kDa
- Gen-ID
- 50489
- UniProt
- Q9UJ71
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