PD-1 Antikörper
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- Target Alle PD-1 (PDCD1) Antikörper anzeigen
- PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser PD-1 Antikörper ist unkonjugiert
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Applikation
- Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunofluorescence (IF), Staining Methods (StM), Immunostaining (ISt)
- Aufreinigung
- Purified by Protein A/G
- Immunogen
- Recombinant full-length human PDCD1 protein
- Klon
- PDCD1-922
- Isotyp
- IgG1 kappa
- Top Product
- Discover our top product PDCD1 Primärantikörper
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- Applikationshinweise
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Positive Control: TY cells. Tonsil.
Known Application: Flow Cytometry (0.5-1 μg/million cells), Immunofluorescence (1-2 μg/mL), Immunohistochemistry (Formalin-fixed) (0.5-1 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues is enhanced by boiling tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0 for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 200 μg/mL
- Buffer
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-80 °C
- Informationen zur Lagerung
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Haltbarkeit
- 24 months
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- Target
- PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))
- Andere Bezeichnung
- PDCD1 (PDCD1 Produkte)
- Synonyme
- CD279 antikoerper, PD-1 antikoerper, PD1 antikoerper, SLEB2 antikoerper, hPD-1 antikoerper, hPD-l antikoerper, Ly101 antikoerper, Pdc1 antikoerper, programmed cell death 1 antikoerper, PDCD1 antikoerper, Pdcd1 antikoerper
- Hintergrund
- PDCD-1 (programmed cell death-1 protein), also designated CD279, is a type I transmembrane receptor and a member of the immunoglobin gene superfamily. It is expressed on activated T-cells, B-cells, and myeloid cells. Anti-PDCD-1 is a marker of angioimmunoblastic lymphoma and suggests a unique cell of origin for this neoplasm. Unlike CD10 and BCL6, PDCD-1 is expressed by few B-cells, so anti-PDCD-1 may be a more specific and useful diagnostic marker in angioimmunoblastic lymphoma. In addition, PDCD-1 expression provides evidence that angioimmunoblastic lymphoma is a neoplasm derived from germinal center-associated T-cells.
- Molekulargewicht
- 55kDa
- Gen-ID
- 5133
- UniProt
- Q15116
- Pathways
- Cancer Immune Checkpoints
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