Plakophilin 1 Antikörper (N-Term)

Produktnummer ABIN6940317

Produktdetails anti-Plakophilin 1 Antikörper

Target: Plakophilin 1 (PKP1)

Bindungsspezifität: N-Term

Reaktivität: Human, Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Plakophilin 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)

Spezifität: Recognizes a protein of 75 kDa, identified as Plakophilin-1. Its epitope maps between aa 1-27 human Plakophilin-1. Plakophilins 1, 2, 3 and 4 (PKP1-4) influence development and participate in linking cadherins to cytoskeletal intermediate filaments. Plakophilins 1-4 contain arm-repeat (armadillo) domains and localize to nuclei and cell desmosomes (cell-cell junctions found in suprabasal layers of stratifying epithelia that undergo mechanical stress). Plakophilin 2 is important for desmosome assembly and is an essential morphogenic factor and architectural component of the heart.

Aufreinigung: Purified by Protein A/G

Immunogen: N-terminus of human Plakophilin-1 protein

Klon: 10B2

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise:

Positive Control: U87, HeLa and A431 cells.

Known Application: Flow Cytometry (0.5-1 μg/million cells), Immunofluorescence (1-2 μg/mL), Western Blot (0.5-1.0 μg/mL)Optimal dilution for a specific application should be determined.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-80 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu Plakophilin 1

Target: Plakophilin 1 (PKP1)

Andere Bezeichnung: PKP1 (PKP1 Produkte)

Synonyme: PKP1 antikoerper, fb30d08 antikoerper, wu:fb30d08 antikoerper, AI528551 antikoerper, B6P antikoerper, plakophilin 1 antikoerper, plakophilin 1b antikoerper, PKP1 antikoerper, pkp1b antikoerper, Pkp1 antikoerper

Molekulargewicht: 75kDa

Gen-ID: 5317

UniProt: Q13835