ENAH Antikörper (AA 485-589)
Kurzübersicht für ENAH Antikörper (AA 485-589) (ABIN6940390)
Target
Alle ENAH Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 485-589
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Aufreinigung
- Purified by Protein A/G
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Immunogen
- Recombinant fragment of human MENA protein (around aa 485-589) (exact sequence is proprietary)
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Isotyp
- IgG2c kappa
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Applikationshinweise
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Positive Control: MCF-7 cells. Uterus.
Known Application: ELISA (For coating, order Ab without BSA),Western Blot (1-2 μg/mL)Optimal dilution for a specific application should be determined.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 200 μg/mL
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Buffer
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-80 °C
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Informationen zur Lagerung
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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Haltbarkeit
- 24 months
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- ENAH (Enabled Homolog (ENAH))
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Andere Bezeichnung
- ENAH
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Hintergrund
- The Wiskott-Aldrich syndrome (WAS) is characterized by thrombocytopenia, eczema, defects in cell-mediated and humoral immunity and a propensity for lymphoproliferative diseases. The syndrome is the result of a mutation in the gene encoding a proline-rich protein termed WASP. WASP is a downstream effector of Cdc42 and has been implicated in actin polymerization and cyto- skeletal organization. Distantly related proteins, VASP (vasodilator-stimulated phosphoprotein) and Mena (for mammalian enabled protein), are involved in the regulation of cytoskeletal dynamics. Both Mena and VASP accumulate at focal adhesions. Mena is highly expressed in the developing nervous system and may be involved in growth cone motility and axon guidance.
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Molekulargewicht
- 80/88/140kDa
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Gen-ID
- 55740
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UniProt
- Q8N8S7
Target
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