STAT2 Antikörper
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- Target Alle STAT2 Antikörper anzeigen
- STAT2 (Signal Transducer and Activator of Transcription 2, 113kDa (STAT2))
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser STAT2 Antikörper ist unkonjugiert
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Applikation
- Immunohistochemistry (IHC), Staining Methods (StM)
- Aufreinigung
- Purified by Protein A/G
- Immunogen
- Recombinant full-length human STAT2 protein
- Klon
- STAT2-2650
- Isotyp
- IgG1 kappa
- Top Product
- Discover our top product STAT2 Primärantikörper
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- Applikationshinweise
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Positive Control: Ramos and Jurkat cell lysates. HeLa cell extract. Human lung carcinoma tissue.
Known Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 200 μg/mL
- Buffer
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-80 °C
- Informationen zur Lagerung
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Haltbarkeit
- 24 months
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- Target
- STAT2 (Signal Transducer and Activator of Transcription 2, 113kDa (STAT2))
- Andere Bezeichnung
- STAT2 (STAT2 Produkte)
- Synonyme
- wu:fj84d07 antikoerper, p113 antikoerper, stat2 antikoerper, 1600010G07Rik antikoerper, AW496480 antikoerper, ISGF-3 antikoerper, P113 antikoerper, STAT113 antikoerper, signal transducer and activator of transcription 2 antikoerper, AGAP000099-PA antikoerper, stat2 antikoerper, STAT2 antikoerper, Stat2 antikoerper
- Hintergrund
- Membrane receptor signaling by various ligands, including interferons and growth hormones such as EGF, induces activation of JAK kinases which then leads to tyrosine phosphorylation of the various Stat transcription factors. Stat1 and Stat2 are induced by IFN- is activated by EGF, but not by IL-6. Highest expression of Stat4 is seen in testis and myeloid cells. IL-12 has been identified as an activator of Stat4. Stat5 has been shown to be activated by prolactin and by IL-3. Stat6 is involved in IL-4 activated signaling pathways.
- Molekulargewicht
- 113kDa
- Gen-ID
- 6773
- UniProt
- P52630
- Pathways
- JAK-STAT Signalweg, Hepatitis C, CXCR4-mediated Signaling Events
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