HNF1A Antikörper (AA 214-339)

Produktnummer ABIN6940684

Produktdetails anti-HNF1A Antikörper

Target: HNF1A (HNF1 Homeobox A (HNF1A))

Bindungsspezifität: AA 214-339

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser HNF1A Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC), Coating (Coat), Staining Methods (StM)

Aufreinigung: Purified by Protein A/G

Immunogen: Recombinant fragment (around aa 214-339) of human HNF1A protein (exact sequence is proprietary)

Klon: HNF1A-2087

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise:

Positive Control: Jurkat cells. Small Intestine or Pancreas.

Known Application: ELISA (For coating, order antibody without BSA),Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-80 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu HNF1A

Target: HNF1A (HNF1 Homeobox A (HNF1A))

Andere Bezeichnung: HNF1A (HNF1A Produkte)

Hintergrund: HNF1A belongs to the homeobox protein family and is an essential transcription factor for many hepatic genes involved in detoxification, homeostasis and metabolisms of glucose, lipid, steroid and amino acid. In addition, HNF1A is an important component of the transcriptional networks governing embryonic pancreas development and differentiation. as well as maintaining the growth and function of islet cells in adult. HNF1A (Hepatocyte nuclear factor 1 alpha) is a transcription factor that is known to regulate pancreatic differentiation and maintain homeostasis of endocrine pancreas. Recently, genome-wide association studies have implicatedHNF1Aas a susceptibility gene for pancreatic cancer.

Molekulargewicht: 79kDa

Gen-ID: 6927

UniProt: P20823

Pathways: Hormone Transport, Carbohydrate Homeostasis