Tyrosinase-Related Protein 1 Antikörper

Produktnummer ABIN6940835

Produktdetails anti-Tyrosinase-Related Protein 1 Antikörper

Target: Tyrosinase-Related Protein 1 (TYRP1)

Reaktivität: Human, Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Tyrosinase-Related Protein 1 Antikörper ist unkonjugiert

Applikation: Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))

Spezifität: It reacts with a 75 kDa melanocyte-specific gene product, identified as Tyrosinase-related protein-1 (TRP-1). It is involved in melanin synthesis. TRP1 is present on the melanosomal membranes of melanoma, normal melanocytes and nevi.Recent evidence suggests that TRP-1 is involved in maintaining stability of tyrosinase protein and modulating its catalytic activity. TRP-1 is also involved in maintenance of melanosome ultrastructure and affects melanocyte proliferation and cell death.

Aufreinigung: Purified by Protein A/G

Immunogen: SK-MEL-23 cells

Klon: TA99

Isotyp: IgG2a kappa

Anwendungsinformationen

Applikationshinweise:

Positive Control: SK-MEL-23, SK-MEL-19, SK-MEL-30, SK-MEL-37 cells. Melanoma.

Known Application: Flow Cytometry (0.5-1 μg/million cells), Immunofluorescence (1-2 μg/mL), Immunohistochemistry (Frozen only) (0.5-1 μg/mL for 30 minutes at RT)Optimal dilution for a specific application should be determined.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-80 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu Tyrosinase-Related Protein 1

Target: Tyrosinase-Related Protein 1 (TYRP1)

Andere Bezeichnung: TYRP1 (TYRP1 Produkte)

Synonyme: CAS2 antikoerper, CATB antikoerper, GP75 antikoerper, OCA3 antikoerper, TRP antikoerper, TRP1 antikoerper, TYRP antikoerper, b-PROTEIN antikoerper, LOC397853 antikoerper, Trypsin antikoerper, hm:zeh0659 antikoerper, tyrp1 antikoerper, zgc:100893 antikoerper, B antikoerper, TYRP1 antikoerper, tyrp-1 antikoerper, TRP-1 antikoerper, Tyrp antikoerper, b antikoerper, brown antikoerper, isa antikoerper, tyrosinase related protein 1 antikoerper, protease, serine 1 L homeolog antikoerper, tyrosinase-related protein 1b antikoerper, tyrosinase-related protein 1 antikoerper, tyrosinase-related protein 1 L homeolog antikoerper, tyrosinase-related protein 1a antikoerper, TYRP1 antikoerper, prss1.L antikoerper, tyrp1b antikoerper, Tyrp1 antikoerper, tyrp1.L antikoerper, tyrp1 antikoerper, LOC100136490 antikoerper, tyrp-1 antikoerper, tyrp1a antikoerper

Molekulargewicht: 75kDa

Gen-ID: 7306

UniProt: P17643