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CA9 Antikörper

CA9 Reaktivität: Human, Pferd WB, IHC, IF, FACS, StM Wirt: Maus Monoclonal PN-15 unconjugated
Produktnummer ABIN6940921
  • Target Alle CA9 Antikörper anzeigen
    CA9 (Carbonic Anhydrase IX (CA9))
    Reaktivität
    • 86
    • 25
    • 21
    • 13
    • 5
    • 4
    • 4
    Human, Pferd
    Wirt
    • 70
    • 34
    Maus
    Klonalität
    • 59
    • 45
    Monoklonal
    Konjugat
    • 49
    • 9
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CA9 Antikörper ist unkonjugiert
    Applikation
    • 69
    • 28
    • 27
    • 26
    • 22
    • 14
    • 13
    • 11
    • 10
    • 9
    • 6
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS), Staining Methods (StM)
    Spezifität
    Recognizes a glycoprotein of ~200 kDa, identified as carbonic anhydrase IX (CAIX/gp200). Its epitope resides in the carbohydrate domain of gp200. It shows no significant cross-reactivity with other carbohydrate determinants, such as the Lewis blood group antigens, epithelial membrane antigen, HMFG, and AB blood group antigens. In normal kidney, gp200 is localized along the brush border of the pars convoluta and pars recta segments of the proximal tubule, as well as focally along the luminal surface of Bowman's capsule adjoining the outgoing proximal tubule. Reportedly, gp200 is expressed by 93 % of primary and 84 % of metastatic renal cell carcinomas. This MAb may be useful in the investigations of carcinomas of proximal nephrogenic differentiation especially those showing tubular differentiation.
    Aufreinigung
    Purified by Protein A/G
    Immunogen
    Microsomal fraction of human renal cortical tissue homogenate
    Klon
    PN-15
    Isotyp
    IgG2b kappa
    Top Product
    Discover our top product CA9 Primärantikörper
  • Applikationshinweise

    Positive Control: Normal kidney or renal cell carcinoma.

    Known Application: Flow Cytometry (0.5-1 μg/million cells), Immunofluorescence (1-2 μg/mL), Western Blot (0.5-1 μg/mL), Immunohistochemistry (Formalin-fixed) (0.5-1 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    200 μg/mL
    Buffer
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-80 °C
    Informationen zur Lagerung
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    Haltbarkeit
    24 months
  • Target
    CA9 (Carbonic Anhydrase IX (CA9))
    Andere Bezeichnung
    CA9 (CA9 Produkte)
    Synonyme
    CA9 antikoerper, CAIX antikoerper, Ca9 antikoerper, MN/CA9 antikoerper, MN antikoerper, carbonic anhydrase 9 antikoerper, CA9 antikoerper, CAH9 antikoerper, Car9 antikoerper
    Molekulargewicht
    55kDa
    Gen-ID
    768
    UniProt
    Q16790
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