BAP1 Antikörper (AA 191-326)

Produktnummer ABIN6940957

Produktdetails anti-BAP1 Antikörper

Target: BAP1 (BRCA1 Associated Protein-1 (Ubiquitin Carboxy-terminal Hydrolase) (BAP1))

Bindungsspezifität: AA 191-326

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser BAP1 Antikörper ist unkonjugiert

Applikation: ELISA, Coating (Coat)

Aufreinigung: Purified by Protein A/G

Immunogen: Recombinant human BAP1 protein fragment (around aa 191-326) (exact sequence is proprietary)

Klon: BAP1-2431

Isotyp: IgG2c kappa

Anwendungsinformationen

Applikationshinweise:

Positive Control: Jurkat or PC-3 or HepG2 cells. Testis, Placenta, Ovarian or Breast Carcinoma.

Known Application: ELISA (For coating, order Ab without BSA), Optimal dilution for a specific application should be determined.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-80 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu BAP1

Target: BAP1 (BRCA1 Associated Protein-1 (Ubiquitin Carboxy-terminal Hydrolase) (BAP1))

Andere Bezeichnung: BAP1 (BAP1 Produkte)

Synonyme: HUCEP-13 antikoerper, UCHL2 antikoerper, BAIAP3 antikoerper, 2300006C11Rik antikoerper, AA989761 antikoerper, AW553466 antikoerper, mKIAA0272 antikoerper, uch-x4 antikoerper, hucep-13 antikoerper, hucep-6 antikoerper, uchl2 antikoerper, si:dkey-42i9.9 antikoerper, BRCA1 associated protein 1 antikoerper, Brca1 associated protein 1 antikoerper, BRCA1 associated protein 1 L homeolog antikoerper, BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) antikoerper, BAP1 antikoerper, Bap1 antikoerper, bap1.L antikoerper, bap1 antikoerper

Hintergrund: The BAP1 gene belongs to the ubiquitin C-terminal hydrolase subfamily of de-ubiquitination enzymes that are involved in the removal of ubiquitin from proteins. The encoded enzyme binds to the breast cancer type 1 susceptibility protein (BRCA1) via the RING finger domain of the latter and acts as a tumor suppressor. In addition, the enzyme may be involved in regulation of transcription, regulation of cell cycle and growth, response to DNA damage and chromatin dynamics. Germ line mutations in this gene may be associated with tumor predisposition syndrome (TPDS), which involves increased risk of cancers including malignant mesothelioma, Uveal melanoma and cutaneous melanoma.

Molekulargewicht: 91kDa

Gen-ID: 8314

UniProt: Q92560