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RCAS1 Antikörper

EBAG9 Reaktivität: Human IHC, IF, StM Wirt: Maus Monoclonal CPTC-EBAG9-1 unconjugated
Produktnummer ABIN6941019
  • Target Alle RCAS1 (EBAG9) Antikörper anzeigen
    RCAS1 (EBAG9) (Estrogen Receptor Binding Site Associated, Antigen, 9 (EBAG9))
    Reaktivität
    • 38
    • 32
    • 13
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 43
    • 8
    • 2
    Maus
    Klonalität
    • 44
    • 9
    Monoklonal
    Konjugat
    • 27
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser RCAS1 Antikörper ist unkonjugiert
    Applikation
    • 24
    • 16
    • 13
    • 13
    • 8
    • 5
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    Immunohistochemistry (IHC), Immunofluorescence (IF), Staining Methods (StM)
    Aufreinigung
    Purified by Protein A/G
    Immunogen
    Recombinant human full-length EBAG9 protein
    Klon
    CPTC-EBAG9-1
    Isotyp
    IgG2c kappa
    Top Product
    Discover our top product EBAG9 Primärantikörper
  • Applikationshinweise

    Positive Control: MCF-7, Jurkat, 293 cell lysates, Human skeletal muscle tissue.

    Known Application: Immunofluorescence (1-2 μg/mL),Immunohistochemistry (Formalin-fixed) (0.5-1 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    200 μg/mL
    Buffer
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-80 °C
    Informationen zur Lagerung
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    Haltbarkeit
    24 months
  • Target
    RCAS1 (EBAG9) (Estrogen Receptor Binding Site Associated, Antigen, 9 (EBAG9))
    Andere Bezeichnung
    EBAG9 (EBAG9 Produkte)
    Synonyme
    EB9 antikoerper, PDAF antikoerper, MGC56608 antikoerper, zgc:56608 antikoerper, MGC84425 antikoerper, EBAG9 antikoerper, AI835379 antikoerper, Rcas1 antikoerper, RCAS1 antikoerper, eb9 antikoerper, pdaf antikoerper, rcas1 antikoerper, estrogen receptor binding site associated, antigen, 9 antikoerper, estrogen receptor binding site associated, antigen, 9 L homeolog antikoerper, estrogen receptor-binding fragment-associated gene 9 antikoerper, EBAG9 antikoerper, ebag9 antikoerper, ebag9.L antikoerper, Ebag9 antikoerper
    Hintergrund
    EBAG9, also known as RCAS1, is an estrogen-transcribed protein. Soluble and membranous RCAS1 proteins may play a role in the immune escape of tumor cells by promoting T lymphocyte inhibition of growth and apoptosis. RCAS1 is expressed in a wide variety of cancers, including uterine, ovarian, and lung cancer cells, and acts as a ligand for a putative receptor present on peripheral lymphocytes. RCAS1 is highly expressed not only in cancer cells but also in non-tumor bile duct cells subject to immune attack. RCAS1 inhibits the in vitro growth of receptor-expressing cells and induces apoptosis, contributing to the ability of tumor cells to evade host immune surveillance. High expression of RCAS1 significantly correlates with tumor progression and with poor outcome for many cancer patients.
    Molekulargewicht
    32kDa
    Gen-ID
    9166
    UniProt
    O00559
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