CD5 Antikörper (AA 269-366)

Produktnummer ABIN6941057

Produktdetails anti-CD5 Antikörper

Target: CD5

Bindungsspezifität: AA 269-366

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD5 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunofluorescence (IF), Staining Methods (StM)

Spezifität: Recognizes a 67 kDa transmembrane protein, which is identified as CD5. The CD5 antigen is found on 95 % of thymocytes and 72 % of peripheral blood lymphocytes. In lymph nodes, the main reactivity is observed in T cell areas. Anti-CD5 is a pan T-cell marker that also reacts with a range of neoplastic B-cells, e.g. chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL), mantle cell lymphoma, and a subset (~10 %) of diffuse large B-cell lymphoma. CD5 aberrant expression is useful in making a diagnosis of mature T-cell neoplasms. Anti-CD5 detection is diagnostic in CLL/SLL within a panel of other B-cell markers, especially one that includes anti-CD23. Anti-CD5 is also very useful in differentiating among mature small lymphoid cell malignancies. In addition, anti-CD5 can be used in distinguishing thymic carcinoma (+) from thymoma (-). Anti-CD5 does not react with granulocytes or monocytes.

Aufreinigung: Purified by Protein A/G

Immunogen: Recombinant fragment of human CD5 protein (around aa 269-366) (exact sequence is proprietary)

Klon: CD5-2418

Isotyp: IgG2c kappa

Anwendungsinformationen

Applikationshinweise:

Positive Control: 293T, Ramos or MOLT-4 cells. Tonsil or Lymph Node.

Known Application: Flow Cytometry (1-2 μg/million cells),Immunofluorescence (1-2 μg/mg), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-80 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu CD5

Target: CD5

Andere Bezeichnung: CD5 (CD5 Produkte)

Synonyme: CD5 antikoerper, Ly-1 antikoerper, Ly-12 antikoerper, Ly-A antikoerper, Lyt-1 antikoerper, LEU1 antikoerper, T1 antikoerper, CD5 molecule antikoerper, CD5 antigen antikoerper, CD5 molecule like antikoerper, Cd5 molecule antikoerper, CD5 antikoerper, Cd5 antikoerper, CD5L antikoerper

Molekulargewicht: 67kDa

Gen-ID: 921

UniProt: P06127