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Rekombinanter CD27 Antikörper

CD27 Reaktivität: Human FACS, IHC, StM Wirt: Maus Monoclonal rLPFS2-1611 unconjugated Recombinant Antibody
Produktnummer ABIN6941125
  • Target Alle CD27 Antikörper anzeigen
    CD27 (CD27 Molecule (CD27))
    Antikörpertyp
    Recombinant Antibody
    Reaktivität
    • 191
    • 75
    • 52
    • 9
    • 5
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 109
    • 89
    • 23
    • 11
    • 4
    • 1
    • 1
    Maus
    Klonalität
    • 145
    • 91
    • 2
    Monoklonal
    Konjugat
    • 82
    • 24
    • 23
    • 15
    • 13
    • 6
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CD27 Antikörper ist unkonjugiert
    Applikation
    • 155
    • 77
    • 50
    • 37
    • 35
    • 24
    • 17
    • 14
    • 13
    • 13
    • 10
    • 9
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Immunohistochemistry (IHC), Staining Methods (StM)
    Spezifität
    Recognizes a protein of a disulfide-linked 120 kDa dimer, identified as CD27. It is expressed on the majority of peripheral T cells, medullary thymocytes, memory-type B cells, and natural killer cells. It is a transmembrane phosphoglycoprotein that belongs to the tumor necrosis factor receptor (TNFR) superfamily. CD27 binds to its ligand CD70, a member of the TNF family, and induces T-cell co-stimulation and B-cell activation. It also interacts with TRAFs and is involved in activation of NFkB and SAPK/JNK and induces apoptosis.
    Aufreinigung
    Purified by Protein A/G
    Immunogen
    Recombinant human CD22 protein (exact sequence is proprietary)
    Klon
    RLPFS2-1611
    Isotyp
    IgG1 kappa
    Top Product
    Discover our top product CD27 Primärantikörper
  • Applikationshinweise

    Positive Control: Ramos cells. Human peripheral blood lymphocytes. Human tonsil and lymph node.

    Known Application: Flow Cytometry (1-2 μg/million cells),Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Tris buffer with 1 mM EDTA, pH 9.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    200 μg/mL
    Buffer
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-80 °C
    Informationen zur Lagerung
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    Haltbarkeit
    24 months
  • Target
    CD27 (CD27 Molecule (CD27))
    Andere Bezeichnung
    CD27 (CD27 Produkte)
    Molekulargewicht
    120kDa
    Gen-ID
    939
    UniProt
    P26842
    Pathways
    Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
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