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CD28 Antikörper

CD28 Reaktivität: Human FACS, IF, Func Wirt: Maus Monoclonal CB28 unconjugated
Produktnummer ABIN6941130
  • Target Alle CD28 Antikörper anzeigen
    CD28
    Reaktivität
    • 178
    • 132
    • 58
    • 34
    • 22
    • 16
    • 12
    • 12
    • 7
    • 7
    • 5
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 145
    • 77
    • 34
    • 18
    • 8
    • 3
    • 2
    Maus
    Klonalität
    • 209
    • 72
    • 3
    Monoklonal
    Konjugat
    • 98
    • 32
    • 29
    • 22
    • 17
    • 6
    • 6
    • 6
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CD28 Antikörper ist unkonjugiert
    Applikation
    • 213
    • 92
    • 58
    • 48
    • 40
    • 31
    • 31
    • 26
    • 21
    • 17
    • 13
    • 7
    • 7
    • 6
    • 6
    • 5
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Immunofluorescence (IF), Functional Studies (Func)
    Spezifität
    Recognizes a glycoprotein of 44-88 kDa, which is identified as CD28. It is the critical T-cell co-stimulatory receptor which provides to the cell the important second activation signal by binding CD80 and CD86 that are expressed by antigen presenting cells. Besides its co-stimulation role, CD28 functions in preventing T-cells from anergic hyporesponsive state or from undergoing premature apoptotic cell death. CD28 is also expressed on human fetal NK cells and some NK cell lines, whereas on murine NK cells the CD28 expression is much broader.
    Aufreinigung
    Purified by Protein A/G
    Immunogen
    Recombinant human CD28 protein
    Klon
    CB28
    Isotyp
    IgG1 kappa
    Top Product
    Discover our top product CD28 Primärantikörper
  • Applikationshinweise

    Positive Control: Jurkat cells. Human lymph nodes and tonsils.

    Known Application: Flow Cytometry (1-2 μg/million cells), ,Immunofluorescence (1-2 μg/mL), ,Functional Studies (Order Ab without BSA & Azide), ,Optimal dilution for a specific application should be determined.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    200 μg/mL
    Buffer
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-80 °C
    Informationen zur Lagerung
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    Haltbarkeit
    24 months
  • Target
    CD28
    Andere Bezeichnung
    CD28 (CD28 Produkte)
    Synonyme
    Tp44 antikoerper, CD28RNA antikoerper, cd28 antikoerper, CD28 molecule antikoerper, CD28 antigen antikoerper, Cd28 molecule antikoerper, CD28 molecule L homeolog antikoerper, CD28 antikoerper, Cd28 antikoerper, cd28.L antikoerper
    Molekulargewicht
    44kDa (monomer), 88kDa (dimer)
    Gen-ID
    940
    UniProt
    P10747
    Pathways
    T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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