IL-10RA Antikörper

Produktnummer ABIN6941467

Produktdetails anti-IL-10RA Antikörper

Target: IL-10RA (IL10RA) (Interleukin 10 Receptor, alpha (IL10RA))

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser IL-10RA Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunofluorescence (IF), Neutralization (Neut)

Spezifität: This monoclonal antibody recognizes Mouse Interleukin-10 receptor 1 (IL-10R1), a cell surface glycoprotein of approximately 110KDa. Its epitope is localized in the ligand-binding domain in the extracellular region of Mouse IL-10R1. This antibody blocks the binding of IL-10 to its receptor. IL-10R1 is a class II cytokine receptor expressed on thymocytes, T cells, B cells, NK cells, monocytes and macrophages. Binding of IL-10 to its receptor initiates JAK/STAT signaling that leads to B cell proliferation and inhibition of macrophage activation.

Keine Kreuzreaktivität: Human

Aufreinigung: Purified by Protein A/G

Immunogen: Purified recombinant extracellular region of Mouse IL10RA

Klon: 1B1-3a

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise:

Positive Control: MPBMC's. Spleen, Thymus, Lymph Node, Placenta, Lung or Liver.

Known Application: Neutralization Studies (Order Ab without Azide),Flow Cytometry (0.5-1 μg/million cells in 0.1ml), Immunofluorescence (0.5-1 μg/mL)Optimal dilution for a specific application should be determined.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-80 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu IL-10RA

Target: IL-10RA (IL10RA) (Interleukin 10 Receptor, alpha (IL10RA))

Andere Bezeichnung: IL-10R1 (Interleukin-10 Receptor 1) (CD210) (IL10RA Produkte)

Synonyme: IL10R1 antikoerper, IL10RA antikoerper, CD210 antikoerper, CD210a antikoerper, CDW210A antikoerper, HIL-10R antikoerper, IL-10R1 antikoerper, IL10R antikoerper, AW553859 antikoerper, CDw210 antikoerper, CDw210a antikoerper, Il10r antikoerper, mIL-10R antikoerper, interleukin 10 receptor subunit alpha antikoerper, interleukin 10 receptor, alpha antikoerper, IL10RA antikoerper, Il10ra antikoerper

Molekulargewicht: 90-110kDa

Gen-ID: 16154

UniProt: Q61727

Pathways: Growth Factor Binding