CBX7 Antikörper
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- Target Alle CBX7 Antikörper anzeigen
- CBX7 (Chromobox Homolog 7 (CBX7))
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Monoklonal
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Konjugat
- Dieser CBX7 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Flow Cytometry (FACS)
- Kreuzreaktivität
- Human
- Aufreinigung
- Purified by Protein A.
- Immunogen
- Recombinant protein within human cbx7 aa 1-150
- Klon
- 5C5
- Isotyp
- IgG
- Top Product
- Discover our top product CBX7 Primärantikörper
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- Applikationshinweise
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WB 1:300-5000
FCM 1:20-100 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- CBX7 (Chromobox Homolog 7 (CBX7))
- Andere Bezeichnung
- CBX7 (CBX7 Produkte)
- Synonyme
- 1600014J01Rik antikoerper, AI851678 antikoerper, D15Ertd417e antikoerper, zgc:110152 antikoerper, chromobox 7 antikoerper, chromobox homolog 7a antikoerper, CBX7 antikoerper, Cbx7 antikoerper, cbx7a antikoerper
- Hintergrund
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Synonyms: Chromobox protein homolog 7, CBX7.
Background: CBX7 (Chromobox protein homolog 7) is a 251 amino acid nuclear protein that contains one N-terminal chromodomain and one C-terminal Pc box. Highly expressed in kidney, brain, heart and skeletal muscle, with weaker expression in peripheral blood leukocytes, CBX7 functions as a component of the chromatin-associated polycomb complex (PcG) and is involved in maintaining the transcriptionally repressed state of target genes. Additionally, CBX7 modifies chromatin and is thought to extend the cellular life span of epithelial cells by repressing p14 ARF expression, while simultaneously repressing telomerase activity. Due to its ability to repress the transcription of cell-cycle-related proteins, CBX7 is thought to play a role in tumorigenesis, specifically in the development of follicular lymphoma and thyroid cancer.
- Gen-ID
- 23492
- UniProt
- O95931
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