CLASP1 Antikörper

Produktnummer ABIN6942580

Produktdetails anti-CLASP1 Antikörper

Target: CLASP1 (Cytoplasmic Linker Associated Protein 1 (CLASP1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser CLASP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Flow Cytometry (FACS)

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: Recombinant protein within human CLASP1 aa 1-200.

Klon: 2B11

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
FCM 1:20-100
IHC-P 1:200-400
IF(IHC-P) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu CLASP1

Target: CLASP1 (Cytoplasmic Linker Associated Protein 1 (CLASP1))

Andere Bezeichnung: CLASP1 (CLASP1 Produkte)

Synonyme: Xorbit antikoerper, clasp1 antikoerper, clasp1b antikoerper, mast1 antikoerper, CLASP1 antikoerper, 1700030C23Rik antikoerper, 5730583A19Rik antikoerper, B130045P17Rik antikoerper, mKIAA0622 antikoerper, MAST1 antikoerper, cytoplasmic linker associated protein 1 S homeolog antikoerper, cytoplasmic linker associated protein 1b antikoerper, cytoplasmic linker associated protein 1 antikoerper, CLIP-associating protein 1 antikoerper, CLIP associating protein 1 antikoerper, clasp1.S antikoerper, clasp1b antikoerper, CLASP1 antikoerper, clasp1 antikoerper, LOC100078792 antikoerper, Clasp1 antikoerper

Hintergrund:

Synonyms: CLIP-associating protein 1, Cytoplasmic linker-associated protein 1, Multiple asters homolog 1, Protein Orbit homolog 1, hOrbit1, CLASP1, KIAA0622, MAST1

Background: Microtubule plus-end tracking protein that promotes the stabilization of dynamic microtubules. Involved in the nucleation of noncentrosomal microtubules originating from the trans-Golgi network (TGN). Required for the polarization of the cytoplasmic microtubule arrays in migrating cells towards the leading edge of the cell. May act at the cell cortex to enhance the frequency of rescue of depolymerizing microtubules by attaching their plus-ends to cortical platforms composed of ERC1 and PHLDB2. This cortical microtubule stabilizing activity is regulated at least in part by phosphatidylinositol 3-kinase signaling. Also performs a similar stabilizing function at the kinetochore which is essential for the bipolar alignment of chromosomes on the mitotic spindle.

Gen-ID: 23332

UniProt: Q7Z460

Pathways: Microtubule Dynamics, M Phase, Maintenance of Protein Location