CTU2 Antikörper (AA 301-400) (Biotin)
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- Target Alle CTU2 Antikörper anzeigen
- CTU2 (Cytosolic Thiouridylase Subunit 2 (CTU2))
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Bindungsspezifität
- AA 301-400
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Reaktivität
- Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser CTU2 Antikörper ist konjugiert mit Biotin
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Kreuzreaktivität
- Maus
- Homologie
- Human,Rat,Cow,Sheep,Horse
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human CTU2/C16orf84
- Isotyp
- IgG
- Top Product
- Discover our top product CTU2 Primärantikörper
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- Applikationshinweise
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WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C for 12 months.
- Haltbarkeit
- 12 months
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- Target
- CTU2 (Cytosolic Thiouridylase Subunit 2 (CTU2))
- Andere Bezeichnung
- CTU2 (CTU2 Produkte)
- Synonyme
- C16orf84 antikoerper, NCS2 antikoerper, UPF0432 antikoerper, Ncs2 antikoerper, 2310061F22Rik antikoerper, cytosolic thiouridylase subunit 2 antikoerper, CTU2 antikoerper, Ctu2 antikoerper
- Hintergrund
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Synonyms: C16orf84, ctu2, CTU2_HUMAN, Cytoplasmic tRNA 2-thiolation protein 2, cytosolic thiouridylase subunit 2 homolog (S. pombe), NCS2, PF0432.
Background: CTU2 is a 515 amino acid cytoplasmic protein that plays a role in the 2-thiolation of mcm(5)S(2)U at wobble positions of tRNA. CTU2 forms a complex with CTU1 and Urm1, and may also form a separate heterodimer with CTU1 to ligate sulfur from thiocarboxylated Urm1 onto tRNA. Existing as three alternatively spliced isoforms, the gene encoding CTU2 maps to human chromosome 16q24.3. Chromosome 16 encodes over 900 genes and comprises nearly 3 % of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, as is Crohn's disease, which is a gastrointestinal inflammatory condition.
- Gen-ID
- 348180
- UniProt
- Q2VPK5
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