DENND1A Antikörper (AA 42-140) (Cy3)

Produktnummer ABIN6942853

Produktdetails anti-DENND1A Antikörper (Cy3)

Target: DENND1A (DENN/MADD Domain Containing 1A (DENND1A))

Bindungsspezifität: AA 42-140

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DENND1A Antikörper ist konjugiert mit Cy3

Applikation: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Ratte

Homologie: Human,Mouse,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human DENND1A

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu DENND1A

Target: DENND1A (DENN/MADD Domain Containing 1A (DENND1A))

Andere Bezeichnung: DENND1A (DENND1A Produkte)

Synonyme: RGD1307927 antikoerper, FAM31A antikoerper, KIAA1608 antikoerper, RP11-230L22.3 antikoerper, 6030446I19Rik antikoerper, connecdenn antikoerper, fam31a antikoerper, DENN domain containing 1A antikoerper, DENN/MADD domain containing 1A antikoerper, DENN domain-containing protein 1A antikoerper, DENN domain containing 1A S homeolog antikoerper, Dennd1a antikoerper, DENND1A antikoerper, dennd1a antikoerper, LOC100512328 antikoerper, dennd1a.S antikoerper

Hintergrund:

Synonyms: Connecdenn 1, Connecdenn, DEN1A_HUMAN, DENN domain-containing protein 1A, DENN/MADD domain containing 1A, dennd1a, FAM31A, FLJ21129, FLJ38464, KIAA1608, OTTHUMP00000022090, Protein FAM31A, RP11 230L22.3.

Background: Clathrin (see MIM 118955)-mediated endocytosis is a major mechanism for internalization of proteins and lipids. Members of the connecdenn family, such as DENND1A, function as guanine nucleotide exchange factors (GEFs) for the early endosomal small GTPase RAB35 (MIM 604199) and bind to clathrin and clathrin adaptor protein-2 (AP2, see MIM 601024). Thus, connecdenns link RAB35 activation with the clathrin machinery (Marat and McPherson, 2010 [PubMed 20154091]).[supplied by OMIM, Nov 2010]

Gen-ID: 57706

UniProt: Q8TEH3