DNASE1L2 Antikörper (AA 201-299)

Produktnummer ABIN6943057

Produktdetails anti-DNASE1L2 Antikörper

Target: DNASE1L2 (Deoxyribonuclease I-Like 2 (DNASE1L2))

Bindungsspezifität: AA 201-299

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DNASE1L2 Antikörper ist unkonjugiert

Applikation: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), ELISA, Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Kreuzreaktivität: Ratte

Homologie: Human,Mouse,Cow,Sheep,Pig,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human DNASE1L2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu DNASE1L2

Target: DNASE1L2 (Deoxyribonuclease I-Like 2 (DNASE1L2))

Andere Bezeichnung: DNASE1L2 (DNASE1L2 Produkte)

Synonyme: DNAS1L2 antikoerper, 4733401H14Rik antikoerper, deoxyribonuclease 1 like 2 antikoerper, deoxyribonuclease 1-like 2 antikoerper, deoxyribonuclease-1-like 2 antikoerper, DNASE1L2 antikoerper, Dnase1l2 antikoerper, LOC100232225 antikoerper

Hintergrund:

Synonyms: Deoxyribonuclease I-like 2, Deoxyribonuclease-1-like 2, DNase I homolog protein DHP1, DNase I-like 2, Dnase1l2, DNSL2_HUMAN.

Background: DNASE1L2 is a 299 amino acid secreted protein that is expressed in brain tissue and shares sequence similarity with DNase I, suggesting a possibly role in DNA hydrolysis. The gene encoding DNASE1L2 maps to human chromosome 16, which encodes over 900 genes and comprises nearly 3 % of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, as is Crohn's disease, which is a gastrointestinal inflammatory condition.

Gen-ID: 1775

UniProt: Q92874