DROSHA Antikörper
-
- Target Alle DROSHA Antikörper anzeigen
- DROSHA (Drosha, Ribonuclease Type III (DROSHA))
-
Reaktivität
- Human
-
Wirt
- Kaninchen
-
Klonalität
- Monoklonal
-
Konjugat
- Dieser DROSHA Antikörper ist unkonjugiert
-
Applikation
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Flow Cytometry (FACS)
- Kreuzreaktivität
- Human
- Aufreinigung
- Purified by Protein A.
- Immunogen
- Recombinant protein within human Drosha aa 1-150
- Klon
- 5C9
- Isotyp
- IgG
- Top Product
- Discover our top product DROSHA Primärantikörper
-
-
- Applikationshinweise
-
WB 1:300-5000
FCM 1:20-100
IHC-P 1:200-400
IF(IHC-P) 1:50-200
IF(ICC) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
- Haltbarkeit
- 12 months
-
- Target
- DROSHA (Drosha, Ribonuclease Type III (DROSHA))
- Andere Bezeichnung
- Drosha (DROSHA Produkte)
- Synonyme
- im:7150667 antikoerper, zgc:158612 antikoerper, ETOHI2 antikoerper, HSA242976 antikoerper, RANSE3L antikoerper, RN3 antikoerper, RNASE3L antikoerper, RNASEN antikoerper, 1110013A17Rik antikoerper, AI874853 antikoerper, Etohi2 antikoerper, Rn3 antikoerper, Rnasen antikoerper, RGD1307626 antikoerper, ribonuclease type III, nuclear antikoerper, Ribonuclease 3 antikoerper, ribonuclease 3 antikoerper, drosha ribonuclease III antikoerper, drosha, ribonuclease type III antikoerper, rnasen antikoerper, Thicy_0885 antikoerper, Sinme_0866 antikoerper, Isova_2087 antikoerper, Sphch_0770 antikoerper, DROSHA antikoerper, Drosha antikoerper
- Hintergrund
-
Synonyms: Ribonuclease 3, Protein Drosha, Ribonuclease III, p241, RNase III, DROSHA, RN3, RNASE3L, RNASEN.
Background: Ribonuclease III double-stranded (ds) RNA-specific endoribonuclease that is involved in the initial step of microRNA (miRNA) biogenesis. Component of the microprocessor complex that is required to process primary miRNA transcripts (pri-miRNAs) to release precursor miRNA (pre-miRNA) in the nucleus. Within the microprocessor complex, DROSHA cleaves the 3' and 5' strands of a stem-loop in pri-miRNAs (processing center 11 bp from the dsRNA-ssRNA junction) to release hairpin-shaped pre-miRNAs that are subsequently cut by the cytoplasmic DICER to generate mature miRNAs. Involved also in pre-rRNA processing. Cleaves double-strand RNA and does not cleave single-strand RNA. Involved in the formation of GW bodies.
- Gen-ID
- 29102
- UniProt
- Q9NRR4
- Pathways
- Regulatorische RNA Pathways
-