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DUSP26 Antikörper (AA 111-211) (Biotin)

DUSP26 Reaktivität: Ratte ELISA, WB, IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal Biotin
Produktnummer ABIN6943139
  • Target Alle DUSP26 Antikörper anzeigen
    DUSP26 (Dual Specificity Phosphatase 26 (DUSP26))
    Bindungsspezifität
    • 15
    • 14
    • 12
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 111-211
    Reaktivität
    • 35
    • 31
    • 7
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    Ratte
    Wirt
    • 58
    • 1
    Kaninchen
    Klonalität
    • 60
    Polyklonal
    Konjugat
    • 18
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser DUSP26 Antikörper ist konjugiert mit Biotin
    Applikation
    • 39
    • 26
    • 26
    • 15
    • 11
    • 9
    • 6
    • 6
    • 5
    • 4
    • 2
    • 2
    • 1
    ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Kreuzreaktivität
    Ratte
    Homologie
    Human,Mouse,Cow,Pig,Horse,Rabbit
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human DUSP26
    Isotyp
    IgG
    Top Product
    Discover our top product DUSP26 Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C for 12 months.
    Haltbarkeit
    12 months
  • Target
    DUSP26 (Dual Specificity Phosphatase 26 (DUSP26))
    Andere Bezeichnung
    DUSP26 (DUSP26 Produkte)
    Synonyme
    DUSP24 antikoerper, LDP-4 antikoerper, MKP8 antikoerper, NATA1 antikoerper, SKRP3 antikoerper, 2310043K02Rik antikoerper, Skrp3 antikoerper, RGD1310090 antikoerper, dual specificity phosphatase 26 antikoerper, dual specificity phosphatase 26 (putative) antikoerper, DUSP26 antikoerper, Dusp26 antikoerper
    Hintergrund

    Synonyms: DSP-4, Dual specificity phosphatase 26 (putative), Dual specificity phosphatase 26, Dual specificity phosphatase SKRP3, Dual specificity protein phosphatase 26, DUS26_HUMAN, DUSP24, DUSP26, Hypothetical protein FLJ31142, LDP 4, LDP-4, Low molecular mass dual specificity phosphatase 4, Low-molecular-mass dual-specificity phosphatase 4, MAP kinase phosphatase 8, MGC1136, MGC2627, Mitogen activated protein kinase phosphatase 8, Mitogen-activated protein kinase phosphatase 8, MKP-8, MKP8, NATA1, NATA1 protein, Novel amplified gene in thyroid anaplastic cancer, SKRP3.

    Background: Mitogen-activated protein (MAP) kinases are a large class of proteins involved in signal transduction pathways, which are activated by a range of stimuli and mediate a number of physiological and pathological changes in the cell. Dual specificity phosphatases (DUSPs) are a subclass of the protein tyrosine phosphatase (PTP) gene superfamily, which are selective for dephosphorylating critical phosphothreonine and phosphotyrosine residues within MAP kinases. DUSP gene expression is induced by a host of growth factors and/or cellular stresses, thereby negatively regulating MAP kinase superfamily members including MAPK/ERK, SAPK/JNK and p38. DUSP26, also designated LDP4, MKP8, NATA1 and SKRP3, is ubiquitously expressed in brain except in the hippocampus. DUSP26 dephosphorylates p38 thereby inhibiting p38-mediated apoptosis in anaplastic thyroid cancer cells. Downregulation of DUSP26 may also contribute to malignant phenotypes of glioma.

    Gen-ID
    78986
    UniProt
    Q9BV47
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