DUSP26 Antikörper (AA 111-211) (AbBy Fluor® 555)
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- Target Alle DUSP26 Antikörper anzeigen
- DUSP26 (Dual Specificity Phosphatase 26 (DUSP26))
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Bindungsspezifität
- AA 111-211
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Reaktivität
- Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser DUSP26 Antikörper ist konjugiert mit AbBy Fluor® 555
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Applikation
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Kreuzreaktivität
- Ratte
- Homologie
- Human,Mouse,Cow,Pig,Horse,Rabbit
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human DUSP26
- Isotyp
- IgG
- Top Product
- Discover our top product DUSP26 Primärantikörper
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- Applikationshinweise
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- DUSP26 (Dual Specificity Phosphatase 26 (DUSP26))
- Andere Bezeichnung
- DUSP26 (DUSP26 Produkte)
- Synonyme
- DUSP24 antikoerper, LDP-4 antikoerper, MKP8 antikoerper, NATA1 antikoerper, SKRP3 antikoerper, 2310043K02Rik antikoerper, Skrp3 antikoerper, RGD1310090 antikoerper, dual specificity phosphatase 26 antikoerper, dual specificity phosphatase 26 (putative) antikoerper, DUSP26 antikoerper, Dusp26 antikoerper
- Hintergrund
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Synonyms: DSP-4, Dual specificity phosphatase 26 (putative), Dual specificity phosphatase 26, Dual specificity phosphatase SKRP3, Dual specificity protein phosphatase 26, DUS26_HUMAN, DUSP24, DUSP26, Hypothetical protein FLJ31142, LDP 4, LDP-4, Low molecular mass dual specificity phosphatase 4, Low-molecular-mass dual-specificity phosphatase 4, MAP kinase phosphatase 8, MGC1136, MGC2627, Mitogen activated protein kinase phosphatase 8, Mitogen-activated protein kinase phosphatase 8, MKP-8, MKP8, NATA1, NATA1 protein, Novel amplified gene in thyroid anaplastic cancer, SKRP3.
Background: Mitogen-activated protein (MAP) kinases are a large class of proteins involved in signal transduction pathways, which are activated by a range of stimuli and mediate a number of physiological and pathological changes in the cell. Dual specificity phosphatases (DUSPs) are a subclass of the protein tyrosine phosphatase (PTP) gene superfamily, which are selective for dephosphorylating critical phosphothreonine and phosphotyrosine residues within MAP kinases. DUSP gene expression is induced by a host of growth factors and/or cellular stresses, thereby negatively regulating MAP kinase superfamily members including MAPK/ERK, SAPK/JNK and p38. DUSP26, also designated LDP4, MKP8, NATA1 and SKRP3, is ubiquitously expressed in brain except in the hippocampus. DUSP26 dephosphorylates p38 thereby inhibiting p38-mediated apoptosis in anaplastic thyroid cancer cells. Downregulation of DUSP26 may also contribute to malignant phenotypes of glioma.
- Gen-ID
- 78986
- UniProt
- Q9BV47
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